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Found 24 with Last Name = 'sheffer' and Initial = 'j'
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194360((E)-thyl-1-methyl-6,7-dihydro-1H-indol-4(5H)-one O...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194358((E)--2-methyl-6,7-dihydro-1H-indol-4(5H)-one O-phe...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194321((E)-2-(3-ethyl-2-methyl-6,7-dihydro-1H-indol-4(5H)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194319((E)-N-(4-chlorophenyl)-2-(3-ethyl-2-methyl-6,7-dih...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195804(1-[1-(3,4-dimethylphenyl)cyclopropyl]-2-[2-(4-meth...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194318((E)-2-(3-ethyl-2-methyl-6,7-dihydro-1H-indol-4(5H)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194357((E)--2-methyl-6,7-dihydro-1H-indol-4(5H)-one O-4-f...)
Affinity DataIC50:  275nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194325((E)-2-(3-ethyl-2-methyl-6,7-dihydro-1H-indol-4(5H)...)
Affinity DataIC50:  280nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195802(1-(2,3-dimethylphenyl)-2-[2-(4-methoxyphenyl)ethyl...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195800(2-[2-(4-methoxyphenyl)ethyl]-1-[1-(4-methylphenyl)...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194361((E)--2-methyl-6,7-dihydro-1H-indol-4(5H)-one O-4-(...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194362((E)-1-(4-((3-ethyl-1,2-dimethyl-6,7-dihydro-1H-ind...)
Affinity DataIC50:  368nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194324((E)-N-(4-acetylphenyl)-2-(2,3-diethyl-1-methyl-6,7...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194317((E)-N-(4-chlorophenyl)-2-(2,3-dimethyl-6,7-dihydro...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195801(2-[2-(4-methoxyphenyl)ethyl]-1-[1-(4-methylphenyl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194322((E)-N-(4-chlorophenyl)-2-(3-ethyl-2-methyl-6,7-dih...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195805(1-[1-(4-methylphenyl)cyclopropyl]-2-(3-phenylpropy...)
Affinity DataIC50:  480nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194359((E)--2-methyl-6,7-dihydro-1H-indol-4(5H)-one O-2-(...)
Affinity DataIC50:  547nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195803(1-(3,4-dichlorophenyl)-2-[2-(4-methoxyphenyl)ethyl...)
Affinity DataIC50:  550nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194323((E)-2-(3-ethyl-2-methyl-6,7-dihydro-1H-indol-4(5H)...)
Affinity DataIC50:  750nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194320((E)-N-(4-chlorophenyl)-2-(6,7-dihydro-1H-indol-4(5...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194321((E)-2-(3-ethyl-2-methyl-6,7-dihydro-1H-indol-4(5H)...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194358((E)--2-methyl-6,7-dihydro-1H-indol-4(5H)-one O-phe...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194360((E)-thyl-1-methyl-6,7-dihydro-1H-indol-4(5H)-one O...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed