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Found 70 with Last Name = 'shen' and Initial = 'yc'
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267948(CHEMBL4097333)
Affinity DataKi:  3.00E+3nMAssay Description:Antagonist activity at closed state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced curre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50048389(4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]in...)
Affinity DataKi:  4.00E+3nMAssay Description:Antagonist activity at closed state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267953(CHEMBL199872)
Affinity DataKi:  4.00E+3nMAssay Description:Antagonist activity at closed state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50048389(4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]in...)
Affinity DataKi:  5.00E+3nMAssay Description:Antagonist activity at open state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  5.00E+3nMAssay Description:Antagonist activity at closed state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced curre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  6.40E+3nMAssay Description:Antagonist activity at open state of GluA1 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 2 mM glutamateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  7.40E+3nMAssay Description:Antagonist activity at closed state of GluA4 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 100 uM gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267953(CHEMBL199872)
Affinity DataKi:  9.00E+3nMAssay Description:Antagonist activity at open state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  1.14E+4nMAssay Description:Antagonist activity at open state of GluA4 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 3 mM glutamateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  1.32E+4nMAssay Description:Antagonist activity at closed state of GluA1 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 40 to 50 uM ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  1.39E+4nMAssay Description:Antagonist activity at open state of GluA3 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 3 mM glutamateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267948(CHEMBL4097333)
Affinity DataKi:  1.40E+4nMAssay Description:Antagonist activity at open state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced current...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50175229(6-(4-amino-phenyl)-2,3,8,10-tetrahydro-1,4-dioxa-7...)
Affinity DataKi:  2.10E+4nMAssay Description:Antagonist activity at closed state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267951(CHEMBL4071408)
Affinity DataKi:  2.78E+4nMAssay Description:Antagonist activity at closed state of GluA3 (unknown origin) assessed as reduction in glutamate-induced current response in presence of 100 uM gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50175229(6-(4-amino-phenyl)-2,3,8,10-tetrahydro-1,4-dioxa-7...)
Affinity DataKi:  3.30E+4nMAssay Description:Antagonist activity at open state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267947(CHEMBL4088629)
Affinity DataKi:  5.00E+4nMAssay Description:Antagonist activity at open state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced current...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267947(CHEMBL4088629)
Affinity DataKi:  5.00E+4nMAssay Description:Antagonist activity at closed state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced curre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267952(CHEMBL406937)
Affinity DataKi:  9.40E+4nMAssay Description:Antagonist activity at closed state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267952(CHEMBL406937)
Affinity DataKi:  1.64E+5nMAssay Description:Antagonist activity at open state of GFP-tagged GluA2Qflip isoform (unknown origin) expressed in HEK293S cells assessed as reduction in glutamate-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334076(CHEMBL1644792 | zhankuic acid A methyl ester)
Affinity DataIC50:  600nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359852(CHEMBL1928925)
Affinity DataIC50:  950nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334075(CHEMBL1258116 | methyl 4alpha-methylergost-8,24(28...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334078(CHEMBL1641973 | Camphoratin J | methyl 3,11-dioxo-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359851(CHEMBL1928924)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334077(CHEMBL1641969 | Camphoratin F | methyl 7beta-hydro...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334079(CHEMBL1644795 | methyl antcinate H)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334061(CHEMBL1644789 | Zhankuic acid A)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359855(CHEMBL1928928)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334062(CHEMBL1644793 | antcin A)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334063(7beta,14alpha-dihydroxy-3,11-dioxo-4alpha-methyler...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359848(CHEMBL1928921)
Affinity DataIC50:  5.44E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334064((1S,2R,5R,6R,9R,10R,13S,15S)-5-[(2R,3E,5R)-5,6-dim...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359853(CHEMBL1928926)
Affinity DataIC50:  7.04E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334065(CHEMBL1644788 | antrocamphin A)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359850(CHEMBL1928923)
Affinity DataIC50:  8.09E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359858(CHEMBL1929082)
Affinity DataIC50:  8.65E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334066(CHEMBL1644790 | Zhankuic acid B)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334067(Benzocamphorin B | CHEMBL1644787)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334068(CHEMBL1641972 | Camphoratin I | [(25S)-26-hydroxye...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334069(3alpha,7beta-dihydroxy-11-oxo-4alpha-methylergosta...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334070(2,2',5,5'-tetramethoxy-3,4,3',4'-bi-methylenedioxy...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334071(CHEMBL1644791 | Zhankuic acid C)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359859(CHEMBL1929083)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50334072(CHEMBL426367 | eburicol)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359854(CHEMBL1928927)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50242128(CHEMBL511822 | Taraxerol, 8 | taraxerol)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50359849(CHEMBL1928922)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Formosa University

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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