Compile Data Set for Download or QSAR
maximum 50k data
Found 196 with Last Name = 'sheng' and Initial = 'w'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  76.9nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305089(22-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi:  674nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305085(8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305084(7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305084(7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305085(8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305086(21-nitro-7alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305088(22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenote...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305089(22-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305089(22-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305088(22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenote...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305086(21-nitro-7alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305085(8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305084(7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305088(22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenote...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305086(21-nitro-7alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50611953(CHEMBL5289716)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611950(CHEMBL5280689)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50353386(CHEMBL1829763 | US8592410, 88 | US8592410, Compara...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human 11beta-HSD1 incubated for 22 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611946(HSD-016 | Hsd-016)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50611950(CHEMBL5280689)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611953(CHEMBL5289716)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of monkey 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611953(CHEMBL5289716)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Hunan University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of HDAC10 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611951(CHEMBL5289930)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in 3T3-L1 cells incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50373109(CHEMBL406645)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM107664(US8575157, 48)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Hunan University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  5nMAssay Description:Inhibition of HDAC2 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611951(CHEMBL5289930)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM107590(US8575157, 31)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human 11beta-HSD1 incubated for 22 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  6.30nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50611946(HSD-016 | Hsd-016)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))TBA
LigandPNGBDBM50611946(HSD-016 | Hsd-016)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50373108(CHEMBL259523)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50611946(HSD-016 | Hsd-016)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholinesterase(Mus musculus (Mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50373109(CHEMBL406645)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse serum BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Mus musculus (Mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50373108(CHEMBL259523)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse serum BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110alpha/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110alpha/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  22.5nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Mus musculus (mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50373118(CHEMBL406885)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Hunan University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  27nMAssay Description:Inhibition of HDAC6 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50309934(2-(3-Benzoyl-4-hydroxy-1,1-dioxo-1H-1lambda*6*-ben...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human 11beta-HSD1 incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110delta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110delta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
Displayed 1 to 50 (of 196 total ) | Next | Last >>
Jump to: