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Found 62 with Last Name = 'sherborne' and Initial = 'bs'
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM19254(IMP | Inosine | Inosinic acid | US11185100, TABLE ...)
Affinity DataKi:  250nMAssay Description:Inhibitory activity against Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112960((1S,3R)-3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phos...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112565(CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112980((1R,3R)-3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phos...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112568(CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220617(CHEMBL47928)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112966(CHEMBL2372049 | EPQpYEEIPIYL)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112959(CHEMBL29298 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220681(CHEMBL45658)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220682(CHEMBL46358)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-like protein 3(Homo sapiens)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50590128(CHEMBL5183837)
Affinity DataIC50:  500nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220679(CHEMBL45504)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220673(CHEMBL48668)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112973(CHEMBL418579 | Phosphoric acid mono-[4-((S)-2-acet...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112974(CHEMBL29820 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112971(CHEMBL418027 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220616(CHEMBL47830)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112975(CHEMBL282111 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220671(CHEMBL44696)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-like protein 3(Homo sapiens)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50590130(CHEMBL5202730)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112968(CHEMBL413761 | Phosphoric acid mono-{4-[(S)-2-acet...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112972((S)-4-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112964(CHEMBL29564 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112958(CHEMBL281685 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112970(CHEMBL30157 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112969(CHEMBL286989 | Phosphoric acid mono-{4-[(S)-2-acet...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112961(CHEMBL29139 | Phosphoric acid mono-[4-((S)-2-acety...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112981(CHEMBL28638 | Phosphoric acid mono-{4-[(S)-2-acety...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50366781(CHEMBL1790100)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-like protein 3(Homo sapiens)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50590129(CHEMBL5189056)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112979((1S,3S)-3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phos...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220672(CHEMBL416079)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112962((1R,3S)-3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phos...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220615(CHEMBL47067)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112976(CHEMBL416938 | Phosphoric acid mono-{4-[(S)-2-acet...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112977(3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phosphonooxy...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112977(3-({(1S,9S)-9-[(S)-2-Acetylamino-3-(4-phosphonooxy...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220618(CHEMBL45771)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112965(CHEMBL441774 | Phosphoric acid mono-{4-[(S)-2-acet...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-like protein 3(Homo sapiens)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112963(CHEMBL29723 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-like protein 3(Homo sapiens)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50590131(CHEMBL5179818)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112570(CHEMBL279957 | N-tert-Butyl-N'-[4-(4-methyl-oxazol...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220683(CHEMBL432699)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220620(CHEMBL297980)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Products

Curated by ChEMBL
LigandPNGBDBM50112957((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220675(CHEMBL47362)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50127715(3-Methoxy-4-oxazol-5-yl-phenylamine | 3-methoxy-4-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112571(CHEMBL27985 | N-tert-Butyl-N'-(4-oxazol-5-yl-pheny...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
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