Affinity DataKi: 8.30nMAssay Description:Antagonist activity at human CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Antagonist activity at human CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair