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Found 1937 with Last Name = 'shim' and Initial = 'i'
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM85052(BIM 23197 | BIM-23197)
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375457(CHEMBL261476)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375451(CHEMBL408579)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019568(Ala-Gly-c(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  0.300nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10860(4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 |...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10860(4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 |...)
Affinity DataKi:  0.300nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  0.300nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237869((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237870(2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM85051(BIM-23190)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50063839(BIM 23268 | CHEMBL263606 | H-cyclo[DCys-Phe-Phe-DT...)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237874((+/-)-2-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-3-(2...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82465(BIM 23023 | BIM-23023 | D-Phe-L-Cys(1)-L-Tyr-D-Trp...)
Affinity DataKi:  0.420nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237872(2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237870(2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375452(CHEMBL262092)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50059090(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Affinity DataKi:  0.560nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237869((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237874((+/-)-2-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-3-(2...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82470(3-(2-Naphtyl)-D-Ala-L-Cys(1)-L-Tyr-D-Trp-L-Lys-L-V...)
Affinity DataKi:  0.75nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237872(2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375451(CHEMBL408579)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]5-HT from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375457(CHEMBL261476)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]5-HT from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  0.850nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019568(Ala-Gly-c(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-...)
Affinity DataKi:  0.880nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375450(CHEMBL407909 | YM-348)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375450(CHEMBL407909 | YM-348)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM86441(CAS_3045225 | NSC_3045225 | YM348)
Affinity DataKi:  0.890nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM50098102(CHEMBL23350 | Sulfamic acid 4-chloro-phenyl ester)
Affinity DataKi:  1.10nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237875(2-(1,3-bis(2-((R)-2-methylpyrrolidin-1-yl)ethyl)im...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10862(4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...)
Affinity DataKi:  1.10nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10862(4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82253(BIM 23052 | CAS_133073-82-2)
Affinity DataKi:  1.22nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  1.26nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50237875(2-(1,3-bis(2-((R)-2-methylpyrrolidin-1-yl)ethyl)im...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50375458(CHEMBL406851)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  1.40nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  1.40nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019568(Ala-Gly-c(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-...)
Affinity DataKi:  1.43nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Cedars-Sinai Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019568(Ala-Gly-c(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-...)
Affinity DataKi:  1.77nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10859(4-methylbenzene-1-sulfonamide | CHEMBL574 | aromat...)
Affinity DataKi:  1.80nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10870(2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...)
Affinity DataKi:  2nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10870(2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10870(2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...)
Affinity DataKi:  2nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10870(2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10870(2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfo...)
Affinity DataKi:  2nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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