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Found 597 with Last Name = 'shin' and Initial = 'i'
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085048((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(methyl-pyri...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataKi:  0.820nMAssay Description:Binding affinity to PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to PPARalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)
Affinity DataKi:  340nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546080(CHEMBL4746218)
Affinity DataKi:  960nMAssay Description:Binding affinity to PPARalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546080(CHEMBL4746218)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity to PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546080(CHEMBL4746218)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546079(CHEMBL4746258)
Affinity DataKi:  2.41E+3nMAssay Description:Binding affinity to PPARalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546079(CHEMBL4746258)
Affinity DataKi:  2.48E+3nMAssay Description:Binding affinity to PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50546079(CHEMBL4746258)
Affinity DataKi:  2.53E+3nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)
Affinity DataKi:  4.13E+3nMAssay Description:Binding affinity to PPARalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538119(US11253516, Example 21)
Affinity DataIC50:  0.100nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538108(US11253516, Example 10)
Affinity DataIC50:  0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538123(US11253516, Example 25)
Affinity DataIC50:  0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538139(US11253516, Example 41)
Affinity DataIC50:  0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538137(US11253516, Example 39)
Affinity DataIC50:  0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538140(US11253516, Example 42)
Affinity DataIC50:  0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538134(US11253516, Example 36)
Affinity DataIC50:  0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538125(US11253516, Example 27)
Affinity DataIC50:  0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538138(US11253516, Example 40)
Affinity DataIC50:  0.400nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538120(US11253516, Example 22)
Affinity DataIC50:  0.400nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596834(CHEMBL5181852)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596831(CHEMBL5177100)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596832(CHEMBL5198569)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596833(CHEMBL5193966)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596834(CHEMBL5181852)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50525939(Balversa | Erdafitinib | Jnj-42756493)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596831(CHEMBL5177100)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596832(CHEMBL5198569)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596833(CHEMBL5193966)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596834(CHEMBL5181852)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596833(CHEMBL5193966)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596833(CHEMBL5193966)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596832(CHEMBL5198569)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596831(CHEMBL5177100)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM538136(US11253516, Example 38)
Affinity DataIC50:  0.5nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596852(CHEMBL5193739)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596833(CHEMBL5193966)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant FAK (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596831(CHEMBL5177100)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596832(CHEMBL5198569)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50596831(CHEMBL5177100)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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