BindingDB PrimarySearch_ki

Found 2790 with Last Name = 'shin' and Initial = 'k'

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM221048(US9284322, varenicline | US9303017, Varenicline)

Ki: 0.0400nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457085(CHEMBL4203542)

Ki: 0.0500nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.0600nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-9More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457098(CHEMBL4217582)

Ki: 0.0600nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.0600nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair

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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457098(CHEMBL4217582)

Ki: 0.0600nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457084(CHEMBL4217248)

Ki: 0.0700nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50109635((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)

Ki: 0.0800nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair

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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50143729((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.0970nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair

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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50109621(CHEMBL425316 | [4-(4-Amino-phenoxy)-phenyl]-(3-hyd...)

Ki: 0.100nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM50538045(CHEMBL4636163)

Ki: 0.140nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457085(CHEMBL4203542)

Ki: 0.150nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM50538008(CHEMBL4638732)

Ki: 0.190nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM50538047(CHEMBL4647019)

Ki: 0.200nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM50538046(CHEMBL4647198)

Ki: 0.200nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457093(CHEMBL4212821)

Ki: 0.200nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457099(CHEMBL4213177)

Ki: 0.210nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457093(CHEMBL4212821)

Ki: 0.220nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457097(CHEMBL4205884)

Ki: 0.25nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457092(CHEMBL4207914)

Ki: 0.260nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457103(CHEMBL4217668)

Ki: 0.270nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457087(CHEMBL4205341)

Ki: 0.280nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457105(CHEMBL4212278)

Ki: 0.300nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457092(CHEMBL4207914)

Ki: 0.300nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457097(CHEMBL4205884)

Ki: 0.300nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Matrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50109626(Biphenyl-4-yl-(3-hydroxycarbamoyl-3,4-dihydro-1H-i...)

Ki: 0.310nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair

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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50143729((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.350nMAssay Description:Inhibition of human recombinant matrix metalloprotease 3More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL

PNG

BDBM50538027(CHEMBL4644169)

Ki: 0.370nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457086(CHEMBL4215754)

Ki: 0.400nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457098(CHEMBL4217582)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Disintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)

Ki: 0.400nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457104(CHEMBL4217235)

Ki: 0.400nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Disintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)

Ki: 0.400nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457091(CHEMBL4207104)

Ki: 0.400nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457107(CHEMBL4209408)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457085(CHEMBL4203542)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457107(CHEMBL4209408)

Ki: 0.420nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457087(CHEMBL4205341)

Ki: 0.420nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50141575((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)

Ki: 0.430nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-3More data for this Ligand-Target Pair

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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457086(CHEMBL4215754)

Ki: 0.440nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457101(CHEMBL4210241)

Ki: 0.5nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457101(CHEMBL4210241)

Ki: 0.5nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457091(CHEMBL4207104)

Ki: 0.5nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

PNG

BDBM50457094(CHEMBL4204531)

Ki: 0.5nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50109621(CHEMBL425316 | [4-(4-Amino-phenoxy)-phenyl]-(3-hyd...)

Ki: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair

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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.510nMAssay Description:Inhibition of human recombinant matrix metalloprotease 3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)

Ki: 0.510nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Stromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL

PNG

BDBM50109635((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)

Ki: 0.530nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Disintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)

Ki: 0.530nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzymeMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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Disintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL

PNG

BDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)

Ki: 0.530nMAssay Description:Inhibition of human tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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Displayed 1 to 50 (of 2790 total ) | Next | Last >>

Filter my 2790 hits

Targets 127▿
- Corticotropin-releasing factor receptor 1 258
- 5-hydroxytryptamine receptor 4 247
- Inhibitor of nuclear factor kappa-B kinase subunit beta 122
- Muscarinic acetylcholine receptor M1 113
- Sphingosine 1-phosphate receptor 2 103
- 5-hydroxytryptamine receptor 6 94
- Disintegrin and metalloproteinase domain-containing protein 17 76
- Dual specificity protein kinase TTK 71
- Matrix metalloproteinase-9 70
- Stromelysin-1 70
- Interstitial collagenase 70
- Adenosine receptor A2a 69
- Neuronal acetylcholine receptor subunit alpha-4/beta-2 67
- Cytochrome P450 3A4 63
- Potassium voltage-gated channel subfamily H member 2 60
- Cytochrome P450 2D6 57
- Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 53
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 47
- Beta-secretase 1 47
- Acetylcholinesterase 47
- Cholinesterase 47
- Lysophosphatidic acid receptor 1 44
- Amyloid-beta precursor protein 44
- Thromboxane A2 receptor 44
- Prolyl endopeptidase 37
- Peroxisome proliferator-activated receptor delta 36
- Disintegrin and metalloproteinase domain-containing protein 9 35
- Peroxisome proliferator-activated receptor alpha 34
- RAF proto-oncogene serine/threonine-protein kinase 34
- Voltage-dependent T-type calcium channel subunit alpha-1G 29
- Peroxisome proliferator-activated receptor gamma 28
- Adenosine receptor A1 28
- Glutathione S-transferase P 23
- Dual specificity mitogen-activated protein kinase kinase 1 22
- Telomerase reverse transcriptase 21
- Glutathione S-transferase A2 21
- Adenosine receptor A3 20
- 2-5A-dependent ribonuclease 20
- Neuronal acetylcholine receptor subunit alpha-3/beta-4 17
- Lysosomal alpha-glucosidase 16
- Cathepsin B 16
- Sphingosine 1-phosphate receptor 3 15
- Advanced glycosylation end product-specific receptor 15
- Cytochrome P450 2C9 15
- Bile acid receptor 13
- Metabotropic glutamate receptor 5 13
- E-selectin 12
- Fanconi anemia group J protein 12
- Lysophosphatidic acid receptor 2 12
- L-selectin 12
- P-selectin 12
- Mitogen-activated protein kinase 8 12
- Glutathione S-transferase Mu 1 10
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 10
- 5-hydroxytryptamine receptor 2A 9
- Adenosine receptor A2b 9
- 40S ribosomal protein S27 9
- Dioxygenase 8
- ATP-dependent DNA helicase DinG 8
- Seed linoleate 13S-lipoxygenase-1 7
- Cytochrome P450 1A2 7
- Cytochrome P450 2C19 7
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 6
- Aldehyde dehydrogenase, cytosolic 1 5
- Mitogen-activated protein kinase 11 5
- Mitogen-activated protein kinase 10 5
- Mitogen-activated protein kinase 9 5
- Mitogen-activated protein kinase 14 5
- Amphiregulin 5
- Histone deacetylase 1 5
- Transient receptor potential cation channel subfamily V member 1 4
- Histamine H3 receptor 4
- Proteasome assembly chaperone 3 4
- Albumin 4
- 5-hydroxytryptamine receptor 7 4
- Cytochrome P450 2C8 4
- Cytochrome P450 2A6 4
- Sphingosine 1-phosphate receptor 4 3
- Sphingosine 1-phosphate receptor 5 3
- Aldehyde dehydrogenase, mitochondrial 3
- Prothrombin 3
- Prostaglandin G/H synthase 1/2 3
- Sphingosine 1-phosphate receptor 1 3
- Serine/threonine-protein kinase PLK1 2
- Protein kinase C epsilon type 2
- Sensor histidine kinase WalK 2
- Sucrase-isomaltase, intestinal 2
- Protein kinase C beta type 2
- Protein kinase C delta type 2
- Protein kinase C gamma type 2
- Protein kinase C eta type 2
- Corticotropin-releasing factor receptor 2 2
- Voltage-dependent L-type calcium channel subunit alpha-1C 2
- Protein kinase C alpha type 2
- DNA topoisomerase 1 2
- Transcriptional regulator ERG 1
- Polyunsaturated fatty acid 5-lipoxygenase 1
- Tyrosyl-DNA phosphodiesterase 1 1
- Serine/threonine-protein kinase mTOR 1
- Tyrosine-protein kinase receptor UFO 1
- Insulin-like growth factor 1 receptor 1
- Epidermal growth factor receptor 1
- Beta-2 adrenergic receptor 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- Beta-1 adrenergic receptor 1
- Protein-tyrosine kinase 6 1
- Hepatocyte growth factor receptor 1
- ALK tyrosine kinase receptor 1
- Nuclear receptor subfamily 1 group I member 2 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1
- Insulin receptor 1
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1
- Receptor-type tyrosine-protein kinase FLT3 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3 1
- Proteasome assembly chaperone 1/2 1
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1
- Macrophage-stimulating protein receptor 1
- Tyrosine-protein kinase ABL1 1
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1
- Focal adhesion kinase 1 1
- Cyclin-dependent kinase 2 1
- Alpha-amylase 1
- Cyclin-dependent kinase 1 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1
- Epithelial discoidin domain-containing receptor 1 1
- 5-hydroxytryptamine receptor 2B 1
- Tissue alpha-L-fucosidase 1
- ...
Publications 50▿
- J Med Chem 45: 919-29 (2002) 172
- J Med Chem 63: 2833-2853 (2020) 111
- J Med Chem 59: 5823-46 (2016) 94
- Eur J Med Chem 103: 289-301 (2015) 88
- Eur J Med Chem 53: 190-202 (2012) 87
- US Patent US8530504 (2013) 83
- Bioorg Med Chem Lett 25: 1479-82 (2015) 80
- US Patent US10308620 (2019) 74
- ACS Med Chem Lett 8: 835-840 (2017) 68
- J Med Chem 43: 2196-203 (2000) 64
- J Med Chem 61: 4993-5008 (2018) 60
- J Med Chem 55: 5255-69 (2012) 55
- J Med Chem 54: 8574-81 (2011) 54
- Bioorg Med Chem Lett 25: 4481-6 (2015) 53
- Bioorg Med Chem Lett 22: 5668-74 (2012) 52
- J Med Chem 55: 8838-58 (2012) 47
- Bioorg Med Chem Lett 27: 4331-4335 (2017) 45
- Bioorg Med Chem Lett 9: 401-6 (1999) 44
- US Patent US9636335 (2017) 44
- ACS Med Chem Lett 4: 1059-63 (2013) 43
- J Med Chem 58: 1760-75 (2015) 41
- Bioorg Med Chem 20: 6559-78 (2012) 41
- J Med Chem 37: 2071-8 (1994) 37
- Bioorg Med Chem Lett 13: 2737-40 (2003) 36
- US Patent US10294217 (2019) 35
- Bioorg Med Chem Lett 17: 1466-70 (2007) 35
- J Med Chem 45: 930-6 (2002) 33
- ACS Med Chem Lett 1: 340-344 (2010) 33
- J Med Chem 56: 4343-56 (2013) 32
- ACS Med Chem Lett 8: 1281-1286 (2017) 32
- Bioorg Med Chem Lett 21: 346-9 (2010) 31
- Bioorg Med Chem Lett 21: 5910-5 (2011) 31
- Bioorg Med Chem Lett 23: 673-8 (2013) 31
- J Enzyme Inhib Med Chem 27: 443-50 (2012) 30
- J Med Chem 47: 1930-8 (2004) 30
- Bioorg Med Chem Lett 22: 5372-8 (2012) 29
- ACS Med Chem Lett 5: 309-14 (2014) 29
- Bioorg Med Chem Lett 25: 4387-92 (2015) 29
- Bioorg Med Chem Lett 26: 1120-3 (2016) 28
- Bioorg Med Chem Lett 22: 4756-61 (2012) 27
- J Med Chem 55: 8450-63 (2012) 26
- Bioorg Med Chem Lett 21: 3002-6 (2011) 26
- Eur J Med Chem 188: (2020) 25
- Bioorg Med Chem Lett 26: 1209-13 (2016) 24
- J Med Chem 39: 1339-43 (1996) 24
- Bioorg Med Chem Lett 23: 6223-7 (2013) 22
- Proc Natl Acad Sci U S A 104: 17347-52 (2007) 21
- Eur J Med Chem 157: 691-704 (2018) 21
- Bioorg Med Chem Lett 18: 4424-7 (2008) 20
- Bioorg Med Chem Lett 13: 2741-4 (2003) 20
- ...
Institutions 26▿
- Suven Life Sciences 473
- Eisai 178
- Nippon Organon K.K. 172
- Ono Pharmaceutical 165
- Chugai Pharmaceutical 125
- The Maharaja Sayajirao University Of Baroda 94
- Korea Institute Of Science And Technology 92
- Seoul National University 87
- Eisai R&D Management 83
- The Catholic University Of Korea 81
- Zeria Pharmaceutical 81
- Shionogi Pharmaceutical Research Center 73
- Advinus Therapeutics 68
- National Institute Of Diabetes 64
- Hokkaido Collaboration Center 56
- Academia Sinica 54
- Korea University 52
- Shionogi 47
- Korea Institute Of Science And Technology (Kist) 46
- Sumitomo Dainippon Pharma 45
- Organon K.K. 33
- TBA 33
- Hokkaido Collaboration Center N-21 30
- Institute Of Cancer Research 24
- Institut National De La Sant£ 21
- Institute Of Science And Technology 20
- ...
Affinity: 0.040 to 2.5E+6 nM▿
- Ki 602
- IC50 1690
- Kd 23
- EC50 475
- Affinity ≤ nM
Xtal structures: 31
Docked structures: 1
Catalog Cmpds: 90