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Found 196 with Last Name = 'shindoh' and Initial = 'h'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197690(CHEMBL3976548)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121716((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...)
Affinity DataIC50:  0.390nMAssay Description:In vitro inhibitory activity against candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220561(CHEMBL173370)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197709(CHEMBL3984621)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220562(CHEMBL171506)
Affinity DataIC50:  0.580nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220565(CHEMBL170524)
Affinity DataIC50:  0.710nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197709(CHEMBL3984621)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121720((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220569(CHEMBL422896)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197685(CHEMBL3681278 | US10689705, Compound 1)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220559(CHEMBL422746)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197709(CHEMBL3984621)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197702(CHEMBL3681287)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197691(CHEMBL3891894)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM130903(US10689705, Compound 7 | US8829199, 196)
Affinity DataIC50:  3nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220571(CHEMBL355250)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197685(CHEMBL3681278 | US10689705, Compound 1)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197685(CHEMBL3681278 | US10689705, Compound 1)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219312(CHEMBL158172)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM); 3.7-9.4 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219305(CHEMBL347895)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219303(CHEMBL345893)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219310(CHEMBL155469)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (Nmt)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197709(CHEMBL3984621)
Affinity DataIC50:  4nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197709(CHEMBL3984621)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197703(CHEMBL3981956)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197691(CHEMBL3891894)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219312(CHEMBL158172)
Affinity DataIC50:  5.20nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197691(CHEMBL3891894)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity against Candida albicans Nmt (CaNmt)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197710(CHEMBL3959997)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219303(CHEMBL345893)
Affinity DataIC50:  7.5nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197683(CHEMBL3907479 | US10689705, Compound 49)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219305(CHEMBL347895)
Affinity DataIC50:  8.30nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197683(CHEMBL3907479 | US10689705, Compound 49)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM130903(US10689705, Compound 7 | US8829199, 196)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219310(CHEMBL155469)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197686(CHEMBL3956001)
Affinity DataIC50:  11nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197685(CHEMBL3681278 | US10689705, Compound 1)
Affinity DataIC50:  13nMAssay Description:Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50219308(CHEMBL351774)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  18nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197710(CHEMBL3959997)
Affinity DataIC50:  18nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197712(CHEMBL3676329 | US10689705, Compound 44)
Affinity DataIC50:  19nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM130906(US10689705, Compound 46 | US8829199, 200)
Affinity DataIC50:  21nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197683(CHEMBL3907479 | US10689705, Compound 49)
Affinity DataIC50:  22nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197690(CHEMBL3976548)
Affinity DataIC50:  25nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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