Compile Data Set for Download or QSAR
maximum 50k data
Found 48 with Last Name = 'shinoyama' and Initial = 'm'
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50200120(CHEMBL260091 | CHIR-090 | US10875832, Compound ChI...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501133(CHEMBL3827314)
Affinity DataIC50:  6nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501144(CHEMBL3827965)
Affinity DataIC50:  18nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501136(CHEMBL3827345)
Affinity DataIC50:  20nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501139(CHEMBL3827962)
Affinity DataIC50:  27nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501135(CHEMBL3827305)
Affinity DataIC50:  58nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501145(CHEMBL3828313)
Affinity DataIC50:  130nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501143(CHEMBL3828674)
Affinity DataIC50:  140nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338244(6-(4-fluorobenzyl)-2-ureido-5,6-dihydro-4H-thieno[...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501137(CHEMBL3827730)
Affinity DataIC50:  200nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501146(CHEMBL3827891)
Affinity DataIC50:  260nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501138(CHEMBL3827035)
Affinity DataIC50:  270nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338239(7-(1-(4-amino-2-fluorobenzyl)piperidin-3-yl)-2-ure...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338237(7-(1-(4-chloro-2-fluorobenzyl)piperidin-3-yl)-2-ur...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501134(CHEMBL3827313)
Affinity DataIC50:  510nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501140(CHEMBL3828138)
Affinity DataIC50:  700nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338243(7-(4-fluorobenzyl)-2-ureido-5,7-dihydro-4H-thieno[...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338260(7-(1-(2-fluoro-4-hydroxybenzyl)piperidin-3-yl)-2-u...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501141(CHEMBL3828670)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338238(7-(1-(2,4-difluorobenzyl)piperidin-3-yl)-2-ureido-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338240(7-(1-(2-fluoro-4-methoxybenzyl)piperidin-3-yl)-2-u...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50501142(CHEMBL3828607)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338242(6-propyl-2-ureido-5,6-dihydro-4H-thieno[2,3-e]inda...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338235((+/-)-7-(1-benzylpiperidin-3-yl)-2-ureido-5,7-dihy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338245(7-isopropyl-2-ureido-5,7-dihydro-4H-thieno[2,3-e]i...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338251(7-(pyridin-4-ylmethyl)-2-ureido-5,7-dihydro-4H-thi...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338236(7-(1-(4-chlorobenzyl)piperidin-3-yl)-2-ureido-5,7-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338246(7-butyl-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indaz...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338241(7-propyl-2-ureido-5,7-dihydro-4H-thieno[2,3-e]inda...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338256((+/-)-7-(1-benzylpyrrolidin-3-yl)-2-ureido-5,7-dih...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338259(7-(1-(2,4,5-trifluorobenzyl)piperidin-3-yl)-2-urei...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338248(7-benzyl-2-ureido-5,7-dihydro-4H-thieno[2,3-e]inda...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338249(7-(pyridin-2-ylmethyl)-2-ureido-5,7-dihydro-4H-thi...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338254(7-(2-(benzyl(methyl)amino)ethyl)-2-ureido-5,7-dihy...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338250(7-(pyridin-3-ylmethyl)-2-ureido-5,7-dihydro-4H-thi...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338257(7-(1-benzylpiperidin-4-yl)-2-ureido-5,7-dihydro-4H...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338255(7-(1-benzylazetidin-3-yl)-2-ureido-5,7-dihydro-4H-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338247(7-hexyl-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indaz...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338253(7-(2-(dimethylamino)ethyl)-2-ureido-5,7-dihydro-4H...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338239(7-(1-(4-amino-2-fluorobenzyl)piperidin-3-yl)-2-ure...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338258((+/-)-7-(1-benzylazepan-3-yl)-2-ureido-5,7-dihydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338261(7-(1-(4-acetamido-2-fluorobenzyl)piperidin-3-yl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338252(7-(2-methoxyethyl)-2-ureido-5,7-dihydro-4H-thieno[...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338237(7-(1-(4-chloro-2-fluorobenzyl)piperidin-3-yl)-2-ur...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338238(7-(1-(2,4-difluorobenzyl)piperidin-3-yl)-2-ureido-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338236(7-(1-(4-chlorobenzyl)piperidin-3-yl)-2-ureido-5,7-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338235((+/-)-7-(1-benzylpiperidin-3-yl)-2-ureido-5,7-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338240(7-(1-(2-fluoro-4-methoxybenzyl)piperidin-3-yl)-2-u...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed