Compile Data Set for Download or QSAR
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Found 55 with Last Name = 'shumsky' and Initial = 'j'
TargetOxytocin receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177595((2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[...)
Affinity DataIC50:  12nMAssay Description:Antagonism of OT-induced response at OT receptor in rat uterine stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177599(CHEMBL202447 | [2-chloro-4-(3-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  91.5nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591(CHEMBL203513 | [2-chloro-4-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  183nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177597(CHEMBL203739 | [2-bromo-4-(3-methyl-pyrazol-1-yl)-...)
Affinity DataIC50:  296nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177594(CHEMBL381763 | [2-chloro-4-(5-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  390nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177598((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  413nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177600(CHEMBL205013 | [2-chloro-4-(3-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  475nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  493nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  778nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177601((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  933nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  1.26E+3nMAssay Description:Antagonism of OT-induced response at OT receptor in rat uterine stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591(CHEMBL203513 | [2-chloro-4-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  1.78E+3nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195560(4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydr...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195550(1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-di...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195576(1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-di...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195551(1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluorome...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195567(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195557(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195555(1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-c...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195564(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  5.95E+3nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195577(4-(biphenyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195549(1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-ca...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195561(1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195572(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195585(1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazoli...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411197(CHEMBL2096735)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411197(CHEMBL2096735)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411196(CHEMBL2096736)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411196(CHEMBL2096736)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195583(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195566(1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195559(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411199(CHEMBL2096737)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411199(CHEMBL2096737)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195562(4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dih...)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195584(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411198(CHEMBL2096734)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50411198(CHEMBL2096734)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195578(1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione ...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonism of AVP-induced response at V1a receptor in isolated rat tail arteriesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195554(1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyp...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195568(5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazo...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195569(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50: >4.40E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195575(4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dih...)
Affinity DataIC50: >5.20E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195582(5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazo...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195580(5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazo...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195574(1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...)
Affinity DataIC50: >5.50E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50195570(1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione | CH...)
Affinity DataIC50:  6.85E+4nMAssay Description:Inhibition of MurB activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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