TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine
Curated by ChEMBL
National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-inhibitor complex using varying levels of xanthine as substrate by Line-weav...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine
Curated by ChEMBL
National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine
Curated by ChEMBL
National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataKi: 128nMAssay Description:Inhibition of full length human CDC2 (1 to 298 residues)/human N-terminal GST-tagged CyclinE1 (1 to 410 residues) expressed in baculovirus expression...More data for this Ligand-Target Pair
Affinity DataKi: 500nMpH: 5.0Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataKi: 700nMpH: 5.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 7More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine
Curated by ChEMBL
National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
TargetGlycogen [starch] synthase, muscle(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by ChEMBL
Indiana University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.31E+3nMAssay Description:Competitive inhibition of C-terminal 6His-tagged human GYS1 using UDPG as substrate in presence of G-6-P by 14C-glucose incorporation based Michaelis...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMpH: 5.5Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 7More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMpH: 7.8Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMpH: 7.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMpH: 7.0Assay Description:Initial rate of reaction between Chymotrypsinogen and BzArg p-nitro-anilide in the presence of 400 microM of the compound at pH 7More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMpH: 5.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMpH: 5.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5.5More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMpH: 5.0Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 7.8More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMpH: 5.0Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataKi: >8.00E+6nMpH: 5.0Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0920nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.211nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.25nMAssay Description:Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.255nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.284nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.334nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.479nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.624nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.628nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.864nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.70nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.10nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.20nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 3.5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 3.80nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 4.10nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 4.5nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Aveiro
Curated by ChEMBL
University Of Aveiro
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.40nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 5.90nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 6.30nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 6.30nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair