TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Montclair State University
Curated by ChEMBL
Montclair State University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human p38alpha using FAM-p38tide as substrate by IMAP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase(Toxoplasma gondii)
Tulane University School Of Medicine
Curated by ChEMBL
Tulane University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Toxoplasma gondii recombinant MAPK1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Montclair State University
Curated by ChEMBL
Montclair State University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human JNK1a1 FAM-EGFR-derived peptide as substrate by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human CYP3A4 using testosterone as a substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase(Toxoplasma gondii)
Tulane University School Of Medicine
Curated by ChEMBL
Tulane University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Toxoplasma gondii recombinant MAPK1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human CYP3A4 using testosterone as a substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair