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Found 172 with Last Name = 'silvia' and Initial = 'am'
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182338(2-(5-(4-(furan-2-yl)-3-methylphenyl)-3-(trifluorom...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182352(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(difluorome...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182347(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50:  12nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182339(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50:  13nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182353(2-(3-(difluoromethyl)-5-(3-methyl-4-(thiazol-4-yl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182332(2-(5-(4-(furan-2-yl)phenyl)-3-(trifluoromethyl)-1H...)
Affinity DataIC50:  20nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176545(3-(difluoromethyl)-5-((2R,6S)-2,6-dimethylmorpholi...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against COX2 in feline whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176555(3-(difluoromethyl)-5-(3-methylpiperidin-1-yl)-1-(5...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182345(2-(5-(3-methyl-4-(oxazol-4-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  30nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179600(5-(2-fluorobenzylthio)-1-(5-(methylsulfonyl)pyridi...)
Affinity DataIC50:  40nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182335(2-(5-(3-fluoro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179631(5-(sec-butylthio)-1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182351(2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179598(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(propylthio)-...)
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182334(2-(3-(difluoromethyl)-5-(3-fluoro-4-(furan-2-yl)ph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179596(5-(cyclopentylmethoxy)-1-(5-(methylsulfonyl)pyridi...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179609(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(phenylthio)-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176552(1-(5-(methylsulfonyl)pyridin-2-yl)-5-((tetrahydrof...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182346(2-(5-(3-methyl-4-(oxazol-2-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  65nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179611(5-(cycloheptyloxy)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179616(5-(benzylthio)-1-(5-(methylsulfonyl)pyridin-2-yl)-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179606(5-(cyclobutylmethoxy)-1-(5-(methylsulfonyl)pyridin...)
Affinity DataIC50:  80nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179591(5-(3-methylbutan-2-yloxy)-1-(5-(methylsulfonyl)pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179620(5-((4-methylenecyclohexyl)methoxy)-1-(5-(methylsul...)
Affinity DataIC50: <90nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182333(2-(5-(3-methyl-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176557(5-(3,5-dimethylpiperidin-1-yl)-1-(5-(methylsulfony...)
Affinity DataIC50:  95nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50179602(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(5,6,7,8-tetr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX1 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179621(5-(cyclohexylthio)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50179624(5-(2,3-dimethylphenoxy)-1-(5-(methylsulfonyl)pyrid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX1 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176534(5-(cyclopropylmethylamino)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179592(5-isobutoxy-1-(5-(methylsulfonyl)pyridin-2-yl)-3-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182340(5-(1-(5-(methylsulfonyl)pyridin-2-yl)-3-(trifluoro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176531(1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-ben...)
Affinity DataIC50:  115nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176533(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(thiophen-2-y...)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176554(5-((1,3-dioxolan-2-yl)methylamino)-1-(5-(methylsul...)
Affinity DataIC50:  126nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176544(5-(azepan-1-yl)-3-(difluoromethyl)-1-(5-(methylsul...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176529(6-(4-cyano-5-(neopentylamino)-3-(trifluoromethyl)-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182343(2-(3-(difluoromethyl)-5-(4-(furan-2-yl)phenyl)-1H-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176547(5-(3-methylbutan-2-ylamino)-1-(5-(methylsulfonyl)p...)
Affinity DataIC50:  132nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179601(5-(cyclohex-3-enylmethoxy)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  140nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176542(5-((cis)-2,6-dimethylmorpholino)-1-(5-(methylsulfo...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176540(6-(5-(bicyclo[2.2.1]heptan-2-ylamino)-4-cyano-3-(t...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176545(3-(difluoromethyl)-5-((2R,6S)-2,6-dimethylmorpholi...)
Affinity DataIC50:  140nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176536(5-(bicyclo[2.2.1]heptan-2-ylamino)-1-(5-(methylsul...)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176538(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(piperidin-1-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179595(5-(3-methylcyclopentyloxy)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  160nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182342(5-(methylsulfonyl)-2-(5-(4-(thiazol-4-yl)phenyl)-3...)
Affinity DataIC50:  160nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179624(5-(2,3-dimethylphenoxy)-1-(5-(methylsulfonyl)pyrid...)
Affinity DataIC50:  170nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179608(5-(2-ethoxyethylthio)-1-(5-(methylsulfonyl)pyridin...)
Affinity DataIC50:  170nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50179610(5-(2-methylpentan-3-yloxy)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  170nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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