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Found 29 with Last Name = 'simao' and Initial = 'am'
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataKi:  340nMAssay Description:Inhibition of TNAP using CDP-star as substrate by non-competitive Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataKi:  590nMAssay Description:Inhibition of TNAP using DEA as substrate by non-competitive Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299534(5-Bromo-2-methoxy-N-(quinolin-3-yl)benzenesulfonam...)
Affinity DataIC50:  120nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50:  190nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50:  230nMAssay Description:Inhibition of TNAP right after mixing with enzyme (EI 0:0) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50:  240nMAssay Description:Inhibition of TNAP after 1 hr incubation with enzyme post-dilution (EI 1:0) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50:  270nMAssay Description:Inhibition of TNAP after 1 hr pre-incubation with enzyme (EI 1:1) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299525(5-chloro-2-methoxy-4-methyl-N-(pyridin-3-yl)benzen...)
Affinity DataIC50:  510nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299526(5-chloro-2-ethoxy-N-(pyridin-3-yl)benzenesulfonami...)
Affinity DataIC50:  540nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299535(2-Methoxy-5-methyl-N-(quinolin-3-yl)benzenesulfona...)
Affinity DataIC50:  650nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299527(5-chloro-2-ethoxy-4-methyl-N-(pyridin-3-yl)benzene...)
Affinity DataIC50:  690nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299536(2-Methoxy-4-nitro-N-(quinolin-3-yl)benzenesulfonam...)
Affinity DataIC50:  740nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299524(2,5-Dimethoxy-N-(pyridin-3-yl)benzenesulfonamide |...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299529(4-chloro-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulf...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299528(2-ethoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonami...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299530(5-fluoro-2-methoxy-N-(pyridin-3-yl)benzenesulfonam...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299531(2,5-dimethoxy-4-methyl-N-(pyridin-3-yl)benzenesulf...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299532(4-bromo-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulfo...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299533(2-methoxy-4,5-dimethyl-N-(pyridin-3-yl)benzenesulf...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299537(2-Methoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonam...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299538(2-Methoxy-4-nitro-N-(pyridin-3-yl)benzenesulfonami...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299540(CHEMBL569638 | N-(2,5-dimethoxybenzyl)quinolin-3-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299543(5-Chloro-2-methoxy-N-(quinolin-3-yl)benzenesulfona...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299544(2,5-Dimethoxy-N-(quinolin-6-yl)benzenesulfonamide ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299539(2,5-Dimethoxy-N-(naphthalen-2-yl)benzenesulfonamid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299541(CHEMBL572541 | N-(2,5-Dimethoxyphenyl)quinoline-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299542(3-Methoxy-N-(quinolin-3-yl)benzenesulfonamide | CH...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IAP by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed