Compile Data Set for Download or QSAR
maximum 50k data
Found 26 with Last Name = 'simmons' and Initial = 'k'
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337102((S)-1-(2-(Diphenylmethyl)benzamido)ethaneboronate ...)
Affinity DataKi:  63nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337101((S)-1-(2-(Naphthalen-2-ylcarbonyl)benzamido)ethane...)
Affinity DataKi:  105nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetp2X7 purinoceptor(Canis lupus familiaris)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  10nMAssay Description:Inhibition of dog P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50404070(CHEMBL338117)
Affinity DataIC50:  31nMAssay Description:Inhibition of human P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50:  35nMAssay Description:Compound was tested for the biological activity at the Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50:  75nMAssay Description:Activity at beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337101((S)-1-(2-(Naphthalen-2-ylcarbonyl)benzamido)ethane...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50:  86nMAssay Description:Activity at beta-1 adrenergic receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor(Cavia porcellus)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  130nMAssay Description:Inhibition of guinea pig P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337094((S)-1-(2-Fluoro-6-phenylbenzamido)ethaneboronic ac...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337100((S)-1-(2-[(Phenylsulfonyl)amino]benzamido)ethanebo...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337095((S)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337093((S)-1-(2-Phenylbenzamido)ethaneboronic acid | CHEM...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337092((S)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337091((S)-1-(1-Benzothiophene-5-carboxamido)ethaneboroni...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50:  2.30E+3nMAssay Description:Activity at beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337098((R)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337096((S)-1-(2,6-Dichlorobenzamido)ethaneboronic acid | ...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337099((R)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337090((S)-1-(Naphthalene-2-carboxamido)ethaneboronic aci...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rat P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
TBA

Curated by ChEMBL
LigandPNGBDBM50337097((S)-1-(2-(Propan-2-yl)benzamido)ethaneboronic acid...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50404070(CHEMBL338117)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed