Found 1919 with Last Name = 'simon' and Initial = 'g' 
Affinity DataKi: 0.160nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.270nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant CA9 catalytic domain preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human recombinant CA12 catalytic domain preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of full length human CA2 cytosolic isoform preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]arginine-vasopressin from human Vasopressin V1a receptor after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
