Affinity DataIC50: 750nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataIC50: 1.37E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataIC50: 2.68E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 4.17E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 4.63E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 4.81E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 5.65E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 5.85E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SIRT3 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.29E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 6.51E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 6.83E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 8.48E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.25E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SIRT2 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Fred Hutchinson Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair