Found 57 with Last Name = 'simone' and Initial = 'ca' 
Affinity DataIC50: 8nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma cruzi Cruzain using Z-FR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
Federal University Of Minas Gerais
Curated by ChEMBL
Federal University Of Minas Gerais
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate at 20 uM preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Universidade Federal Do Rio De Janeiro
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
