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Found 112 with Last Name = 'singh' and Initial = 'ab'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93118(PTP1B Inhibitor, 19)
Affinity DataKi:  2.50E+4nM IC50:  6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)
Affinity DataKi:  2.87E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93109(PTP1B Inhibitor, 5)
Affinity DataKi:  3.00E+4nM IC50:  7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93111(PTP1B Inhibitor, 7)
Affinity DataKi:  3.40E+4nM IC50:  8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataKi:  3.42E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)
Affinity DataKi:  3.63E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)
Affinity DataKi:  4.44E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93113(PTP1B Inhibitor, 11)
Affinity DataKi:  4.80E+4nM IC50:  6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93112(PTP1B Inhibitor, 10)
Affinity DataKi:  4.80E+4nM IC50:  6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487368(CHEMBL2259740)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487364(CHEMBL2259741)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93110(PTP1B Inhibitor, 6)
Affinity DataKi:  5.60E+4nM IC50:  9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93116(PTP1B Inhibitor, 14)
Affinity DataKi:  6.30E+4nM IC50:  8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487366(CHEMBL2259730)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93117(PTP1B Inhibitor, 15)
Affinity DataKi:  1.35E+5nM IC50:  1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487365(CHEMBL2259731)
Affinity DataKi:  1.35E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93115(PTP1B Inhibitor, 13)
Affinity DataKi:  1.50E+5nM IC50:  2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487367(CHEMBL2259743)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93114(PTP1B Inhibitor, 12)
Affinity DataKi:  1.70E+5nM IC50:  4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487369(CHEMBL2259742)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  3.55E+5nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346150(5-(2-(2-(1H-pyrrol-1-yl)ethoxy)-4-methoxyphenyl)-3...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346150(5-(2-(2-(1H-pyrrol-1-yl)ethoxy)-4-methoxyphenyl)-3...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346151(4-(2-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)e...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)
Affinity DataIC50:  2.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346151(4-(2-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)e...)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346148(CHEMBL1783773 | N,N-diethyl-2-(5-methoxy-2-(3-phen...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346148(CHEMBL1783773 | N,N-diethyl-2-(5-methoxy-2-(3-phen...)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346166(1-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)-3-(...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346165(1-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)-3-(...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)
Affinity DataIC50:  3.46E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)
Affinity DataIC50:  3.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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