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Found 40 with Last Name = 'sivaraman' and Initial = 'j'
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121305(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121291(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21006((2R)-5-[(diaminomethylidene)amino]-2-[(2R)-3-(meth...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121299(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20998((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-pheny...)
Affinity DataKi:  21nM ΔG°:  -43.8kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20997((2S)-N-[(1R)-4-[(diaminomethylidene)amino]-1-{[(1S...)
Affinity DataKi:  23nM ΔG°:  -43.6kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20999((2R)-2-[(2R)-3-(benzylsulfanyl)-2-[1-(4-phenylphen...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121290(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20993((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-(4-hy...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121286(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  67nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20996((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-(4-hy...)
Affinity DataKi:  112nM ΔG°:  -39.7kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20995((2R)-2-[(2R)-3-(benzylsulfanyl)-2-[1-(4-phenylphen...)
Affinity DataKi:  155nM ΔG°:  -38.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121298(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  160nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121300(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121300(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121301(5-Amino-2-[2-(2-biphenyl-4-yl-acetylamino)-3-methy...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121292(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121288(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121295(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  240nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121293(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  270nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121289(2-{2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulf...)
Affinity DataKi:  270nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21005((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-pheny...)
Affinity DataKi:  460nM ΔG°:  -36.2kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21000((2R)-5-[(diaminomethylidene)amino]-2-[(2R)-3-{[(4-...)
Affinity DataKi:  464nM ΔG°:  -36.1kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121287(2-[2-(2-Biphenyl-4-yl-acetylamino)-pentanoylamino]...)
Affinity DataKi:  490nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21001((2S)-N-[(1R)-4-[(diaminomethylidene)amino]-1-{[(1S...)
Affinity DataKi:  511nM ΔG°:  -35.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121286(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  560nMAssay Description:Specificity of Cathepsin B inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121302(2-(2-{2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methyls...)
Affinity DataKi:  930nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121286(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  1.00E+3nMAssay Description:Specificity of Cathepsin K inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121290(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  2.90E+3nMAssay Description:Specificity of Cathepsin K inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121297(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121291(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  4.10E+3nMAssay Description:Specificity of Cathepsin B inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121291(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  5.90E+3nMAssay Description:Specificity of Cathepsin K inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21002((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-(4-hy...)
Affinity DataKi:  6.00E+3nM ΔG°:  -29.8kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121303(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21003((2R)-5-[(diaminomethylidene)amino]-2-[(2S)-2-forma...)
Affinity DataKi:  1.07E+4nM ΔG°:  -28.4kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121290(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  1.50E+4nMAssay Description:Specificity of Cathepsin B inhibition by the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121294(2-(2-Biphenyl-4-yl-acetylamino)-N*1*-{1-[1-(1-carb...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21004((3S)-3-{[(1R)-4-[(diaminomethylidene)amino]-1-{[(1...)
Affinity DataKi:  5.75E+4nM ΔG°:  -24.2kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121304(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-hydroxy-propi...)
Affinity DataKi:  7.40E+4nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121296(2-(2-{2-[2-(2-Acetylamino-4-methylsulfanyl-butyryl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed