BindingDB PrimarySearch

Found 62 with Last Name = 'skepper' and Initial = 'ck'

DNA gyrase subunit A/B(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50197073(3-amino-7-((R)-3-((S)-1-aminoethyl)pyrrolidin-1-yl...)

IC50: 200nMAssay Description:Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate prei...More data for this Ligand-Target Pair

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DNA gyrase subunit A/B(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542206(CHEMBL4640061)

IC50: 430nMAssay Description:Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate prei...More data for this Ligand-Target Pair

PDB MMDB KEGG
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DNA gyrase subunit A/B(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)

IC50: 490nMAssay Description:Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate prei...More data for this Ligand-Target Pair

PDB MMDB KEGG
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DNA gyrase subunit A/B(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542207(CHEMBL4634552)

IC50: 1.25E+3nMAssay Description:Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate prei...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566539(CHEMBL4860033)

IC50: 2.70E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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DNA gyrase subunit A/B(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542205(CHEMBL4643875)

IC50: 2.91E+3nMAssay Description:Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate prei...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566543(CHEMBL4864037)

IC50: 8.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566541(CHEMBL4867915)

IC50: 1.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566538(CHEMBL4875315)

IC50: 1.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Bifunctional coenzyme A synthase(Homo sapiens)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50263238(CHEMBL4102651)

IC50: 1.10E+4nMAssay Description:Inhibition of human PPATMore data for this Ligand-Target Pair

PDB Reactome pathway
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566542(CHEMBL4878164)

IC50: 1.20E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566546(CHEMBL4875871)

IC50: 1.30E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566544(CHEMBL4852170)

IC50: 1.70E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566545(CHEMBL4861495)

IC50: 1.80E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566510(CHEMBL4860105)

IC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566540(CHEMBL4877922)

IC50: 2.90E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566535(CHEMBL4860370)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566519(CHEMBL4868731)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566517(CHEMBL4873798)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566514(CHEMBL4865462)

IC50: >3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566513(CHEMBL4869164)

IC50: >3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566549(CHEMBL4856534)

IC50: >3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566547(CHEMBL4869998)

IC50: >3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566548(CHEMBL4861063)

IC50: >3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566524(CHEMBL4867992)

IC50: 4.20E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542206(CHEMBL4640061)

IC50: 4.88E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells measured after 10 mins by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542206(CHEMBL4640061)

IC50: 4.90E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by manual patch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Sodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542205(CHEMBL4643875)

IC50: >5.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Sodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542206(CHEMBL4640061)

IC50: >5.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566522(CHEMBL4847738)

IC50: 9.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Sodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566512(CHEMBL4857241)

IC50: 9.20E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566511(CHEMBL4846404)

IC50: 1.09E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542207(CHEMBL4634552)

IC50: 1.14E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells measured for 10 mins by QPatch automated patch-clamp assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid PDB

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566536(CHEMBL4633030)

IC50: 1.14E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by long incubation protocol based Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566523(CHEMBL4851838)

IC50: 1.26E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566537(CHEMBL4874636)

IC50: 1.27E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by long incubation protocol based Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)

IC50: 1.29E+5nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566512(CHEMBL4857241)

IC50: 1.36E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566521(CHEMBL4855694)

IC50: 1.50E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566513(CHEMBL4869164)

IC50: 1.88E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566520(CHEMBL4849541)

IC50: 2.11E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50542205(CHEMBL4643875)

IC50: 2.14E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566514(CHEMBL4865462)

IC50: 2.93E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566518(CHEMBL4855895)

IC50: 2.97E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566534(CHEMBL4869317)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566533(CHEMBL4866375)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566532(CHEMBL4852578)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566531(CHEMBL4860997)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566529(CHEMBL4861982)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

BDBM50566528(CHEMBL4855299)

IC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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