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Found 114 with Last Name = 'slater' and Initial = 'am'
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50010904(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012938(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012937(CHEMBL76697 | Less polar Epimer-6-Cyclohexyl-4-hyd...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012937(CHEMBL76697 | Less polar Epimer-6-Cyclohexyl-4-hyd...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012946(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012944(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012939(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012943(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007355((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-methyl-1...)
Affinity DataIC50:  6.30nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)
Affinity DataIC50:  6.90nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419102(CHEMBL1824369)
Affinity DataIC50:  17.4nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008845(2-(3,4-Dichloro-phenyl)-N-(2,2-dimethyl-1-pyrrolid...)
Affinity DataIC50:  24nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012941(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384248(CHEMBL2030451)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012940(6-Cyclohexyl-4-hydroxy-5-[2-(8-isobutyl-6-phenyl-[...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384249(CHEMBL2030450)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419101(CHEMBL1824368)
Affinity DataIC50:  40.7nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012942(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007361(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  53nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419123(CHEMBL1824371)
Affinity DataIC50:  55.0nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012947(CHEMBL306098 | N-[1-Cyclohexylmethyl-2-hydroxy-5-m...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419103(CHEMBL1824370)
Affinity DataIC50:  69.2nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012945(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008843(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  85nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419105(CHEMBL1824373)
Affinity DataIC50:  85.1nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  96nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419104(CHEMBL1824372)
Affinity DataIC50:  97.7nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419099(CHEMBL1824364)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419100(CHEMBL1824367)
Affinity DataIC50:  126nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419117(CHEMBL1824374)
Affinity DataIC50:  126nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419114(CHEMBL1824363)
Affinity DataIC50:  155nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012936(6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-...)
Affinity DataIC50:  212nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384250(CHEMBL2030448)
Affinity DataIC50:  252nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384252(CHEMBL2029359)
Affinity DataIC50:  262nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384253(CHEMBL2030445)
Affinity DataIC50:  285nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384247(CHEMBL2030436)
Affinity DataIC50:  288nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384251(CHEMBL2030446)
Affinity DataIC50:  303nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419111(CHEMBL1824382)
Affinity DataIC50:  339nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384256(CHEMBL2030447)
Affinity DataIC50:  385nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419110(CHEMBL1824381)
Affinity DataIC50:  398nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419106(CHEMBL1824375)
Affinity DataIC50:  427nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419116(CHEMBL1824608)
Affinity DataIC50:  490nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419097(CHEMBL1824606)
Affinity DataIC50:  501nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419107(CHEMBL1824376)
Affinity DataIC50:  562nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419121(CHEMBL1824605)
Affinity DataIC50:  562nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50384248(CHEMBL2030451)
Affinity DataIC50:  565nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384258(CHEMBL2030443)
Affinity DataIC50:  601nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419119(CHEMBL1824607)
Affinity DataIC50:  617nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419124(CHEMBL1824377)
Affinity DataIC50:  646nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419120(CHEMBL1824379)
Affinity DataIC50:  646nMAssay Description:Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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