Found 100 with Last Name = 'smith' and Initial = 'ka' TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >30nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: >30nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Affinity DataIC50: 191nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Affinity DataIC50: 191nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Negative allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 296nMAssay Description:Negative allosteric modulation of mGlu2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC11 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC4 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC8 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC9 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC1 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC7 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Biotechnology Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC5 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 325nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 358nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 378nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 385nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 587nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 758nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 788nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 793nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 835nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 978nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 984nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMpH: 7.4 T: 2°CAssay Description:The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Institute For Natural Products Applications And Research Technologies
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
