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Found 97 with Last Name = 'smith' and Initial = 'rh'
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300479(3-hydroxy-5-(4-(pyridin-4-yl)phenyl)pentanoic acid...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300470(3-hydroxy-5-(4'-(methylthio)biphenyl-4-yl)pentanoi...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300471(5-(4'-acetylbiphenyl-4-yl)-3-hydroxypentanoic acid...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300480(5-(4-(benzofuran-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50:  181nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300471(5-(4'-acetylbiphenyl-4-yl)-3-hydroxypentanoic acid...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300470(3-hydroxy-5-(4'-(methylthio)biphenyl-4-yl)pentanoi...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300469(5-(4-(9H-fluoren-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300473(2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid | CH...)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300481(5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300478(5-(biphenyl-4-yl)-3-methoxypentanoic acid | CHEMBL...)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300466(5-(4'-(benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300479(3-hydroxy-5-(4-(pyridin-4-yl)phenyl)pentanoic acid...)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50369418(CHEMBL58711 | R-87027)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300474(2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid | CH...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50036586((S)-5-Fluoro-8-methyl-7-(3-methyl-but-2-enyl)-6,7,...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300476(5-(biphenyl-4-yl)-3-oxopentanoic acid | CHEMBL5729...)
Affinity DataIC50:  7.84E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300473(2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid | CH...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300475(2-(2-(biphenyl-4-yl)ethylthio)acetic acid | CHEMBL...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50036599((S)-5,8-Dimethyl-7-(3-methyl-but-2-enyl)-6,7,8,9-t...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300467(3-hydroxy-5-(4'-phenoxybiphenyl-4-yl)pentanoic aci...)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300468(5-(4-(dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypent...)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300469(5-(4-(9H-fluoren-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50:  2.61E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50036570((S)-5-Ethynyl-8-methyl-7-(3-methyl-but-2-enyl)-6,7...)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300468(5-(4-(dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypent...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50036605((S)-5-Methoxy-8-methyl-7-(3-methyl-but-2-enyl)-6,7...)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.66E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300467(3-hydroxy-5-(4'-phenoxybiphenyl-4-yl)pentanoic aci...)
Affinity DataIC50:  4.19E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM1433((11S)-11-methyl-10-(3-methylbut-2-en-1-yl)-1,3,10-...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300480(5-(4-(benzofuran-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50:  5.02E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300481(5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300477(3-acetoxy-5-(biphenyl-4-yl)pentanoic acid | CHEMBL...)
Affinity DataIC50:  5.44E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Western Maryland College

Curated by ChEMBL
LigandPNGBDBM50036595((S)-8-Methyl-7-(3-methyl-but-2-enyl)-1-thioxo-1,2,...)
Affinity DataIC50:  5.63E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300475(2-(2-(biphenyl-4-yl)ethylthio)acetic acid | CHEMBL...)
Affinity DataIC50:  9.52E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300474(2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid | CH...)
Affinity DataIC50:  9.59E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300474(2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid | CH...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300475(2-(2-(biphenyl-4-yl)ethylthio)acetic acid | CHEMBL...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300476(5-(biphenyl-4-yl)-3-oxopentanoic acid | CHEMBL5729...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300477(3-acetoxy-5-(biphenyl-4-yl)pentanoic acid | CHEMBL...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300478(5-(biphenyl-4-yl)-3-methoxypentanoic acid | CHEMBL...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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