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Found 46 with Last Name = 'soares' and Initial = 'mb'
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117291(CHEMBL3613587)
Affinity DataIC50:  8nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50393871(CHEMBL2158234)
Affinity DataIC50:  30nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50393873(CHEMBL2158132)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50114653((1E)-1-(3,4-dichlorophenyl)ethan-1-one thiosemicar...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Trypanosoma cruzi Cruzain using Z-FR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117285(CHEMBL3613583)
Affinity DataIC50:  70nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50:  180nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50393872(CHEMBL2158133)
Affinity DataIC50:  200nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117281(CHEMBL3613582)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330928(2-[(Phenylthio)propylide-1-enehydrazinyl]-5-methyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50282986(CHEMBL3786939)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain preincubated for 10 mins followed by Z-FR-AMC substrate addition measured for 5 mins at 12 secs t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117278(CHEMBL3613569)
Affinity DataIC50:  600nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50516805(CHEMBL3785388)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400185(CHEMBL2180342)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400195(CHEMBL2180344)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400188(CHEMBL2180670)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400197(CHEMBL2180347)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50282987(CHEMBL4165151)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain preincubated for 10 mins followed by Z-FR-AMC substrate addition measured for 5 mins at 12 secs t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400186(CHEMBL2180341)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400187(CHEMBL2180339)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400196(CHEMBL2180340)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400195(CHEMBL2180344)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400194(CHEMBL2180346)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400193(CHEMBL2180345)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400193(CHEMBL2180345)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400192(CHEMBL2180665)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50516806(CHEMBL3787052)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400191(CHEMBL2180349)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate at 20 uM preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330927(2-[(p-Methylphenylthio)ethylidenehydrazinyl]-5-met...)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400189(CHEMBL2180669)
Affinity DataIC50:  3.19E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400187(CHEMBL2180339)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400185(CHEMBL2180342)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400190(CHEMBL2180354)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400189(CHEMBL2180669)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400188(CHEMBL2180670)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400187(CHEMBL2180339)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400186(CHEMBL2180341)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400185(CHEMBL2180342)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin L using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400190(CHEMBL2180354)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400186(CHEMBL2180341)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400188(CHEMBL2180670)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50400189(CHEMBL2180669)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant cathepsin S using ZFR-pNA as substrate preincubated for 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed