Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-inhibitor complex by Li...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-substrate-inhibitor com...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 1.68E+4nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 2.23E+4nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 2.28E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 3.24E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 3.44E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 3.54E+4nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 4.29E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 4.56E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 6.88E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 7.61E+4nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 1.29E+5nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 2.59E+5nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 2.89E+5nMAssay Description:Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysisMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universitat De Barcelona
US Patent
Universitat De Barcelona
US Patent
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universitat De Barcelona
US Patent
Universitat De Barcelona
US Patent
Affinity DataIC50: 0.0800nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair