Compile Data Set for Download or QSAR
maximum 50k data
Found 703 with Last Name = 'soll' and Initial = 'rm'
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070599(2-Chloro-benzenesulfonic acid 3-(4-guanidino-butox...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126647(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149023(3-{[1-({[(diaminomethylidene)amino]oxy}methyl)cycl...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149022(CHEMBL421081 | Oxyguanidine derivative)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083968(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  4.40nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070597(2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-p...)
Affinity DataKi:  4.60nMAssay Description:Compound was evaluated for inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070597(2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-p...)
Affinity DataKi:  4.60nMAssay Description:Anti- Thrombin activity using standard chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070597(2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-p...)
Affinity DataKi:  4.60nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083963(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126640(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  4.80nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149015(CHEMBL122144 | Oxyguanidine derivative)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149020(CHEMBL122696 | Oxyguanidine derivative)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083971(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  6nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126642(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  6.70nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126634(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  6.70nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148990(CHEMBL421243 | Oxyguanidine derivative)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126652(2-METHANESULFONYL-BENZENESULFONIC ACID 3-METHYL-5-...)
Affinity DataKi:  7.70nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148994(CHEMBL421096 | Oxyguanidine derivative)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149008(CHEMBL122205 | Oxyguanidine derivative)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083969(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148988(CHEMBL123028 | Oxyguanidine derivative)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149017(CHEMBL341539 | Oxyguanidine derivative)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083967(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.10nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083966(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.20nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083961(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.40nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126650(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  9.90nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149032(CHEMBL123226 | Oxyguanidine derivative)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148999(CHEMBL121892 | Oxyguanidine derivative)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083964(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064653(2-Chloro-benzenesulfonic acid 3-methyl-5-[2-(methy...)
Affinity DataKi:  11nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083957(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi:  11.9nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126651(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070599(2-Chloro-benzenesulfonic acid 3-(4-guanidino-butox...)
Affinity DataKi:  13nMAssay Description:Compound was evaluated for inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070599(2-Chloro-benzenesulfonic acid 3-(4-guanidino-butox...)
Affinity DataKi:  13nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084068(2-Trifluoromethyl-benzenesulfonic acid 3-(1-carbam...)
Affinity DataKi:  14nMAssay Description:Anti- Thrombin activity using standard chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233679(CHEMBL399284 | N-[3'-(5-carbamimidoyl-2-methylsulf...)
Affinity DataKi:  14nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084080(2-Nitro-benzenesulfonic acid 3-(1-carbamimidoyl-pi...)
Affinity DataKi:  16nMAssay Description:Anti- Thrombin activity using standard chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148987(CHEMBL125772 | Oxyguanidine derivative)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149027(CHEMBL121686 | Oxyguanidine derivative)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149034(CHEMBL124164 | Oxyguanidine derivative)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149019(CHEMBL123453 | Oxyguanidine derivative)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083972(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  20nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233691(4-(2'-amino-6'-methyl-biphenyl-3-sulfonyl)-5-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149000(CHEMBL332660 | Oxyguanidine derivative)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149014(CHEMBL121817 | Oxyguanidine derivative)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149003(CHEMBL123440 | N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233674(6-{3-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophe...)
Affinity DataKi:  22nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084078(2,3-Dichloro-benzenesulfonic acid 3-(1-carbamimido...)
Affinity DataKi:  22nMAssay Description:Anti- Thrombin activity using standard chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 703 total ) | Next | Last >>
Jump to: