BindingDB PrimarySearch

Found 177 with Last Name = 'somers' and Initial = 'f'

cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

IC50: 0.600nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547752(CHEMBL4797113)

IC50: 1.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547793(CHEMBL4741218)

IC50: 1.30nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547769(CHEMBL4758144)

IC50: 1.5nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547790(CHEMBL4754478)

IC50: 1.70nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547765(CHEMBL4783572)

IC50: 2.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547766(CHEMBL4788385)

IC50: 2.60nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547751(CHEMBL4755779)

IC50: 3.40nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547775(CHEMBL4742646)

IC50: 3.5nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547767(CHEMBL4761967)

IC50: 10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547778(CHEMBL4761452)

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547764(CHEMBL4740457)

IC50: 24nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547787(CHEMBL4797527)

PDB Reactome pathway
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3D Structure (crystal)

cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547780(CHEMBL4751598)

IC50: 30nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547782(CHEMBL4745282)

IC50: 38nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547753(CHEMBL4744076)

IC50: 47nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547763(CHEMBL4793775)

IC50: 49nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547779(CHEMBL4793092)

IC50: 50nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547760(CHEMBL4763230)

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547769(CHEMBL4758144)

IC50: 54nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547751(CHEMBL4755779)

IC50: 56nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547750(CHEMBL4800314)

IC50: 66nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547788(CHEMBL4785227)

IC50: 69nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547759(CHEMBL4761206)

IC50: 74nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547780(CHEMBL4751598)

IC50: 78nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547772(CHEMBL4758400)

IC50: 87nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547768(CHEMBL4786145)

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547767(CHEMBL4761967)

IC50: 89nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547776(CHEMBL4764406)

PDB Reactome pathway KEGG
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547770(CHEMBL4796896)

IC50: 91nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

Details Article PubMed

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547765(CHEMBL4783572)

IC50: 100nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

Details Article PubMed

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547783(CHEMBL4757440)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547766(CHEMBL4788385)

IC50: 107nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547791(CHEMBL4798804)

IC50: 110nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547775(CHEMBL4742646)

IC50: 112nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547777(CHEMBL4746828)

IC50: 115nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547792(CHEMBL4796661)

IC50: 155nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547770(CHEMBL4796896)

IC50: 178nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547777(CHEMBL4746828)

IC50: 195nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

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ATP-binding cassette sub-family C member 8(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM50363009(CHEMBL1946412)

IC50: 200nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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GoogleScholar

CHEMBL PC cid PC sid Similars

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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547775(CHEMBL4742646)

IC50: 229nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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ATP-binding cassette sub-family C member 8(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM50363013(CHEMBL191539)

IC50: 240nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547756(CHEMBL4746465)

IC50: 246nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547774(CHEMBL4762723)

IC50: 263nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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ATP-binding cassette sub-family C member 8(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM50363006(CHEMBL363989)

IC50: 280nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Patents Similars

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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547769(CHEMBL4758144)

IC50: 282nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547767(CHEMBL4761967)

IC50: 288nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547762(CHEMBL4799257)

IC50: 324nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547765(CHEMBL4783572)

IC50: 331nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL

BDBM50547755(CHEMBL4777378)

IC50: 339nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

PDB Reactome pathway
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Displayed 1 to 50 (of 177 total ) | Next | Last >>

Filter my 177 hits

Targets 17▿
- cGMP-dependent 3',5'-cyclic phosphodiesterase 44
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 38
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A 36
- ATP-binding cassette sub-family C member 8 30
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B 8
- Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 3
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 3
- ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 2
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1
- Cytochrome P450 1A2 1
- Cytochrome P450 2C9 1
- Cytochrome P450 2C19 1
- Cytochrome P450 2D6 1
- Cytochrome P450 2C8 1
- Cytochrome P450 3A4 1
- ...
Publications 3▿
- J Med Chem 63: 12887-12910 (2020) 145
- J Med Chem 54: 8353-61 (2011) 30
- J Med Chem 53: 147-54 (2010) 2
Institutions 3▿
- Janssen Pharmaceutica N. V. 145
- Universit£ 30
- Universite De Liege 2
Affinity: 0.60 to 5.0E+4 nM▿
- IC50 175
- EC50 2
- Affinity ≤ nM
Xtal structures: 2
Docked structures: 0
Catalog Cmpds: 2