Found 55 with Last Name = 'sommer' and Initial = 'j' TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 0.130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 0.370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.5nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.90nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.20nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro 50% inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]-SND 919 (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 50nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 55nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 60nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 65nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 120nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 174nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme with relative to captopril(=1)More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]-SND 919 (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.10E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.20E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.30E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]-SND 919 (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]-SND 919 (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 4.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]spiroperidol (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+4nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+4nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D1 labeled with [3H]-SCH- 23390 (0.3 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.04E+4nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]spiroperidol (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D1 labeled with [3H]-SCH- 23390 (0.3 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D1 labeled with [3H]-SCH- 23390 (0.3 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D1 labeled with [3H]-SCH- 23390 (0.3 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]spiroperidol (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for binding affinity to Dopamine receptor D2 labeled with [3H]spiroperidol (0.5 nM) in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to recombinant FXR-LBD (unknown origin) expressed in Escherichia coli BL21 (DE3) gold cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to recombinant FXR-LBD (unknown origin) expressed in Escherichia coli BL21 (DE3) gold cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.34E+4nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.25E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
