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Found 25 with Last Name = 'sommer' and Initial = 'p'
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112064(3-(3-Aminomethyl-phenyl)-2-(3-{2-[(2R,5S)-5-({2-[2...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112065(3-(3-Aminomethyl-phenyl)-2-[2-(2-{(2S,5R)-5-[({[2-...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112070(3-(3-Aminomethyl-phenyl)-2-{2-[2-((2R,5S)-5-{2-[2-...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112069(3-(3-Aminomethyl-phenyl)-2-(4-{2-[(2R,5S)-5-({3-[2...)
Affinity DataKi:  350nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112067(CHEMBL175811 | methyl3-(3-aminomethylphenyl)-2-{2-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112068((R)-2-Acetylamino-3-(3-aminomethyl-phenyl)-propion...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112066((R)-2-Acetylamino-3-(4-aminomethyl-phenyl)-propion...)
Affinity DataKi:  2.13E+5nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  3.10E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  1.30E+6nMAssay Description:Inhibition of tissue kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  1.80E+6nMAssay Description:Inhibition of tissue kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  2.00E+6nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  3.30E+6nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391834(CHEMBL2147024)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391830(CHEMBL2147020)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391831(CHEMBL2147021)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391832(CHEMBL2147022)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50036635(CHEMBL3354313)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50036635(CHEMBL3354313)
Affinity DataIC50:  6.71E+3nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) after 3 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50036635(CHEMBL3354313)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50036635(CHEMBL3354313)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391835(CHEMBL2147025)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391833(CHEMBL2147023)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed