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Found 204 with Last Name = 'son' and Initial = 'em'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.700nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118600(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperid...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118601(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-f...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118606(1-(benzofuran-2-ylmethyl)-4-(2-(bis(4-fluorophenyl...)
Affinity DataKi:  1.01nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126823(1-(4-bromobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  1.10nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126814(1-(4-(trifluoromethyl)benzyl)-4-(2-(bis(4-fluoroph...)
Affinity DataKi:  1.10nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126817(4-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperid...)
Affinity DataKi:  1.20nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  1.20nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126813(1-(4-chlorobenzyl)-4-(2-(bis(4-fluorophenyl)methox...)
Affinity DataKi:  1.20nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118605(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-t...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataKi:  1.61nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  2.10nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126822(1-(4-fluorobenzyl)-4-(2-(bis(4-fluorophenyl)methox...)
Affinity DataKi:  2.30nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  2.5nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50098405(4-(2-Benzhydryloxy-ethyl)-1-(4-trifluoromethyl-ben...)
Affinity DataKi:  3.5nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  3.70nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity of the compound towards dopmine transporter(DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055879(4-(2-Benzhydryloxy-ethyl)-1-(4-chloro-benzyl)-pipe...)
Affinity DataKi:  3.80nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126822(1-(4-fluorobenzyl)-4-(2-(bis(4-fluorophenyl)methox...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108815(4-(2-Benzhydryloxy-ethyl)-1-(4-iodo-benzyl)-piperi...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataKi:  5.10nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118603(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(3-pheny...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126816(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(4-m...)
Affinity DataKi:  5.70nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50098393(4-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataKi:  5.70nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  6.40nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108815(4-(2-Benzhydryloxy-ethyl)-1-(4-iodo-benzyl)-piperi...)
Affinity DataKi:  7.20nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126819(1-(4-methoxybenzyl)-4-(2-(bis(4-fluorophenyl)metho...)
Affinity DataKi:  7.90nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50049365(1-Benzyl-4-{2-[bis-(4-fluoro-phenyl)-methoxy]-ethy...)
Affinity DataKi:  9.90nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126818(1-(3-methoxybenzyl)-4-(2-(bis(4-fluorophenyl)metho...)
Affinity DataKi:  13.3nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  13.6nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118602(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  16nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118602(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  16nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118601(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-f...)
Affinity DataKi:  41nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118605(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-t...)
Affinity DataKi:  45nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  47nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126821(1-(2-methoxybenzyl)-4-(2-(bis(4-fluorophenyl)metho...)
Affinity DataKi:  63nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  68nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  73nMAssay Description:Inhibition of [3H]-5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  79nMAssay Description:Inhibition of [3H]-norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118606(1-(benzofuran-2-ylmethyl)-4-(2-(bis(4-fluorophenyl...)
Affinity DataKi:  85nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  88nMAssay Description:Affinity at rat serotonin transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118600(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperid...)
Affinity DataKi:  88nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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