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Found 165 with Last Name = 'sonnenberg' and Initial = 'jd'
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101563(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataKi:  24nMAssay Description:Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101548(3-(4-Benzyloxy-phenyl)-1-(2-hydroxy-1-methyl-2-phe...)
Affinity DataKi:  101nMAssay Description:Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataKi:  477nMAssay Description:Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101543(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataKi:  515nMAssay Description:Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093652(2-Methyl-6-pentyl-4-piperidin-1-yl-5H-pyrrolo[3,2-...)
Affinity DataIC50:  0.200nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093696(6-(3-Fluoro-phenyl)-2-methyl-4-piperidin-1-yl-5H-p...)
Affinity DataIC50:  0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093664(6-(4-Fluoro-phenyl)-2-methyl-4-piperidin-1-yl-5H-p...)
Affinity DataIC50:  0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093646(6-Benzofuran-2-yl-2-methyl-4-piperidin-1-yl-5H-pyr...)
Affinity DataIC50:  0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093691(4-(3,6-Dihydro-2H-pyridin-1-yl)-2-methyl-6-phenyl-...)
Affinity DataIC50:  0.400nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093675(6-(3,5-Difluoro-phenyl)-2-methyl-4-piperidin-1-yl-...)
Affinity DataIC50:  0.400nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101571(1-Methyl-1-(1-methyl-2-pyridin-4-yl-ethyl)-3-(4-ph...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093697(2-Methyl-4-piperidin-1-yl-6-p-tolyl-5H-pyrrolo[3,2...)
Affinity DataIC50:  0.5nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093647(2-Methyl-6-(5-methyl-furan-2-yl)-4-piperidin-1-yl-...)
Affinity DataIC50:  0.5nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093678(2-Methyl-6-phenyl-4-pyrrolidin-1-yl-5H-pyrrolo[3,2...)
Affinity DataIC50:  0.700nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093673(2-Methyl-4-piperidin-1-yl-6-(4-trifluoromethyl-phe...)
Affinity DataIC50:  0.700nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101533(1-[2-(4-Chloro-phenyl)-1-methyl-ethyl]-1-methyl-3-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093683(2-Methyl-6-phenyl-4-piperidin-1-yl-5H-pyrrolo[3,2-...)
Affinity DataIC50:  1.10nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093651(6-Phenyl-4-piperidin-1-yl-5H-pyrrolo[3,2-d]pyrimid...)
Affinity DataIC50:  1.20nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093692(5-Methyl-2-phenyl-7-piperidin-1-yl-1H-pyrrolo[3,2-...)
Affinity DataIC50:  1.70nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093616(4-Azepan-1-yl-2-methyl-6-phenyl-5H-pyrrolo[3,2-d]p...)
Affinity DataIC50:  1.80nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093640(4-(2,5-Dihydro-pyrrol-1-yl)-2-methyl-6-phenyl-5H-p...)
Affinity DataIC50:  2.20nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093672(2-Methyl-4-(2-methyl-piperidin-1-yl)-6-phenyl-5H-p...)
Affinity DataIC50:  3nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101540(1-Methyl-1-(1-methyl-2-phenyl-ethyl)-3-(4-phenoxy-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101559(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-[...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101531(3-Dibenzofuran-2-yl-1-(2-hydroxy-1-methyl-2-phenyl...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101537(3-[4-(4-Chloro-phenoxy)-phenyl]-1-(2-hydroxy-1-met...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093624(2-Methyl-6-phenethyl-4-piperidin-1-yl-5H-pyrrolo[3...)
Affinity DataIC50:  5.30nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101563(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101562(1-(1,2-Diphenyl-ethyl)-1-methyl-3-(4-phenoxy-pheny...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093632(6-Cyclohexylmethyl-2-methyl-4-piperidin-1-yl-5H-py...)
Affinity DataIC50:  8.5nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101549(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093666(6-Butyl-2-methyl-4-piperidin-1-yl-5H-pyrrolo[3,2-d...)
Affinity DataIC50:  10nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093693(6-Cyclohexyl-2-methyl-4-piperidin-1-yl-5H-pyrrolo[...)
Affinity DataIC50:  11nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093704(4-(2,6-Dimethyl-piperidin-1-yl)-2-methyl-6-phenyl-...)
Affinity DataIC50:  17nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093633(2-Methyl-6-phenoxymethyl-4-piperidin-1-yl-5H-pyrro...)
Affinity DataIC50:  18nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093679(2-Ethyl-6-phenyl-4-piperidin-1-yl-5H-pyrrolo[3,2-d...)
Affinity DataIC50:  20nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101548(3-(4-Benzyloxy-phenyl)-1-(2-hydroxy-1-methyl-2-phe...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101547(1-sec-Butyl-1-methyl-3-(4-phenoxy-phenyl)-urea | C...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093700(6-Phenyl-4-piperidin-1-yl-2-propyl-5H-pyrrolo[3,2-...)
Affinity DataIC50:  28nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093662(CHEMBL136650 | Methyl-(6-phenyl-4-piperidin-1-yl-5...)
Affinity DataIC50:  29nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093658(2-Methyl-6-phenyl-4-piperidin-1-yl-furo[3,2-d]pyri...)
Affinity DataIC50:  30nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093684(2-Cyclopropyl-6-phenyl-4-piperidin-1-yl-5H-pyrrolo...)
Affinity DataIC50:  32nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101553(1-Methyl-3-(4-phenoxy-phenyl)-1-(1,2,3,4-tetrahydr...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101554(1-Methyl-1-phenethyl-3-(4-phenoxy-phenyl)-urea | C...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093614(CHEMBL337152 | Diethyl-(2-methyl-6-phenyl-5H-pyrro...)
Affinity DataIC50:  36nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093613(6-(4-Methoxy-phenyl)-2-methyl-4-piperidin-1-yl-5H-...)
Affinity DataIC50:  41nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093618(6-(2-Fluoro-phenyl)-2-methyl-4-piperidin-1-yl-5H-p...)
Affinity DataIC50:  44nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093674(6-Adamantan-1-yl-2-methyl-4-piperidin-1-yl-5H-pyrr...)
Affinity DataIC50:  45nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50093657(CHEMBL137613 | Furan-2-ylmethyl-methyl-(2-methyl-6...)
Affinity DataIC50:  52nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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