Affinity DataKi: 6.80nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 23.6nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 32.4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 39.6nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 47.7nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 58.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 207nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 212nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 235nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 502nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 572nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 593nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 601nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 646nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 825nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 930nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 939nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.11E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.24E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 3.56E+3nMAssay Description:Antagonist activity at histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.22E+3nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.82E+3nMAssay Description:Antagonist activity at histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.36E+4nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 3.49E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+4nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of AChE (unknown origin) assessed as reduction in acetylthiocholine iodide hydrolysis after 15 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of BuChE (unknown origin) by spectrophotometric analysis based Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Inhibition of BuChE (unknown origin) assessed as reduction in S-butyrylthiocholine chloride hydrolysis after 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Massachusetts Boston
Curated by ChEMBL
University Of Massachusetts Boston
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of amyloid beta ((1 to 42) (unknown origin) oligomer assembly after 30 mins by biotinyl-streptavidin assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of BuChE (unknown origin) by spectrophotometric analysis based Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of BuChE (unknown origin) by spectrophotometric analysis based Ellman's assayMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Federal University Of Vi£Osa
Curated by ChEMBL
Federal University Of Vi£Osa
Curated by ChEMBL
Affinity DataIC50: 1.44E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of AChE (unknown origin) by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of BuChE (unknown origin) assessed as reduction in S-butyrylthiocholine chloride hydrolysis after 15 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of AChE (unknown origin) by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of AChE (unknown origin) assessed as reduction in acetylthiocholine iodide hydrolysis after 15 mins by Ellman methodMore data for this Ligand-Target Pair