Found 170 with Last Name = 'sowell' and Initial = 'jw' 
Affinity DataKi: 0.350nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 870nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]methylscopolamine [3H]NMS from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 5.80E+3nMAssay Description:Binding affinity of the compound against mouse Muscarinic acetylcholine receptor M2 using heart tissue and [3H]-N-methylscopolamineMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 9.50E+3nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Ability of the compound to displace [3H]-methylscopolamine ([3H]-NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataKi: 6.60E+4nMAssay Description:Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro Butyrylcholinesterase inhibitory activity of the compound to determine its ability to reverse the cholinergic deficit characteristic of ADMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 23nMAssay Description:The compound was evaluated for the inhibition human of Butyrylcholinesterase IMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of human butryl cholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:In vitro acetyl cholinesterase(AChE-I) inhibitory activity, ability to reverse the cholinergic deficit characteristic of ADMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]-N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissueMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina
Curated by ChEMBL
University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina
Curated by ChEMBL
University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of [3H]-pirenzepine binding to mouse muscarinic acetylcholine receptor M1 from cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of [3H]-N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]-N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissueMore data for this Ligand-Target Pair
