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Found 479 with Last Name = 'spencer' and Initial = 'g'
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601173(CHEMBL5176968)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601180(CHEMBL5170002)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381826(US10272079, Compound 003)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601178(CHEMBL5202545)
Affinity DataIC50:  2nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381826(US10272079, Compound 003)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426615(N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601172(CHEMBL5183104)
Affinity DataIC50:  4nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601178(CHEMBL5202545)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426616(N,N′-(2,2′-(2,2′-(2,2′-(1,...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601181(CHEMBL5170188)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601179(CHEMBL5202068)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601180(CHEMBL5170002)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601179(CHEMBL5202068)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601181(CHEMBL5170188)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426507(N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381824(US10272079, Compound 001)
Affinity DataIC50:  25nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426610(N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601167(CHEMBL5200502)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601177(CHEMBL3906248)
Affinity DataIC50:  32nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426607(N,N′-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,...)
Affinity DataIC50:  32nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241539(CHEMBL4084845)
Affinity DataIC50:  37nMAssay Description:Kinetic constant was measured for PMII of Leishmania donovani promastigotes using supernatant (S12) fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426607(N,N′-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426507(N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601177(CHEMBL3906248)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601176(CHEMBL3971033)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM381824(US10272079, Compound 001)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601165(CHEMBL3950244)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601165(CHEMBL3950244)
Affinity DataIC50:  50nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426610(N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601163(CHEMBL3932557)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601164(CHEMBL5209058)
Affinity DataIC50:  63nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426583(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601168(CHEMBL5207418)
Affinity DataIC50:  63nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601171(CHEMBL5189049)
Affinity DataIC50:  63nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601176(CHEMBL3971033)
Affinity DataIC50:  63nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601167(CHEMBL5200502)
Affinity DataIC50:  79nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426583(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50:  79nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241533(CHEMBL4102775)
Affinity DataIC50:  83nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50550438(CHEMBL4798388)
Affinity DataIC50:  90nMAssay Description:Inhibition of active recombinant human N-terminal His-tagged 11-betaHSD1 expressed in Escherichia coli using cortisone, NADPH and glucose-6-phosphate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601162(CHEMBL5190823)
Affinity DataIC50:  100nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601162(CHEMBL5190823)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601172(CHEMBL5183104)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM426533(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601168(CHEMBL5207418)
Affinity DataIC50:  126nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601171(CHEMBL5189049)
Affinity DataIC50:  158nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601174(CHEMBL5182162)
Affinity DataIC50:  200nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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