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Found 130 with Last Name = 'spillier' and Initial = 'q'
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  2.70E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  4.00E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of PHGDH (unknown origin) by FLINT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195606(NCT-503)
Affinity DataIC50:  2.50E+3nMAssay Description:Non-competitive inhibition of PHGDH (unknown origin) assessed as reduction in NADH formation using 3-phosphoglycerate as substrate after 20 mins in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195606(NCT-503)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232861(CHEMBL2131647 | US11225469, Compound 24)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of PHGDH (unknown origin) expressed in Escherichia coli BL21 using 3-phosphoglycerate as substrate preincubated for 4 hrs followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM58473(MLS001172437 | N-(4-methyl-2-pyridinyl)-4-[3-(trif...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50:  3.30E+4nMAssay Description:Non-competitive inhibition of His6-tagged full length PHGDH (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in NADH f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of PHGDH (unknown origin) expressed in Escherichia coli BL21 using 3 -phosphoglycerate as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50:  3.51E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232878(CHEMBL4095492)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232857(CHEMBL4067810)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232881(CHEMBL4089953)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232870(CHEMBL4071292)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232868(CHEMBL4087786)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232864(CHEMBL4060200)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232863(CHEMBL4082083)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232862(CHEMBL4103667)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50:  5.05E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232860(CHEMBL3125071 | US11225469, Compound 23)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195607(PHGDH-inactive | US11225469, Compound 71)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50:  6.44E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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