Compile Data Set for Download or QSAR
maximum 50k data
Found 100 with Last Name = 'sprecher' and Initial = 'u'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309502(CHEMBL591279 | rac-3-(3-(fluoromethyl)phenyl)-9,10...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309504(CHEMBL598470 | rac-3-(4-(fluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309503(CHEMBL601937 | rac-3-(2,5-dimethylphenyl)-9,10-dim...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309469((R)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309471((R)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309463((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309470((4S)-1-[(2S,3S,11bS)-2-amino-9,10-dimethoxy-1,3,4,...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309464((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309497((2S,3S,11bS)-9,10-dimethoxy-3-(4-methylpyridin-2-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309468((S)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309465((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309462((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309497((2S,3S,11bS)-9,10-dimethoxy-3-(4-methylpyridin-2-y...)
Affinity DataIC50:  19nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309455(1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309454((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309500(CHEMBL591277 | rac-3-(3-cyclopropylphenyl)-9,10-di...)
Affinity DataIC50:  38nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309499(CHEMBL591982 | rac-3-(3-ethylphenyl)-9,10-dimethox...)
Affinity DataIC50:  61nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309459((SR, SR, SR)-9,10-Dimethoxy-3-(1-oxo-1lambda*4*-[1...)
Affinity DataIC50:  142nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309461((SR, SR, SR)-3-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  142nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437885(CHEMBL2407949)
Affinity DataIC50: <200nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437890(CHEMBL2407936 | CHEMBL2407938)
Affinity DataIC50: <200nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309457((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309453((SR, SR, SR)1-(2-amino-9,10-dimethoxy-2,3,4,6,7,11...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309460((SR, SR, SR)-3-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309458((SR, SR, SR)-9,10-Dimethoxy-3-(1-oxo-1lambda*4*-is...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309467((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309501(CHEMBL591278 | rac-3-(3-isopropylphenyl)-9,10-dime...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309456(1-((2R,3R,11bR)-2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309466((SR, SR, SR)-1-(2-amino-9,10-dimethoxy-2,3,4,6,7,1...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human DPP4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437882(CHEMBL2407952)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437881(CHEMBL2407953)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437878(CHEMBL2407929)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437880(CHEMBL2407955)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437883(CHEMBL2407951)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50309498((2R,3R,11bR)-9,10-dimethoxy-3-(4-methylpyridin-2-y...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437872(CHEMBL2407935)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437873(CHEMBL2407934)
Affinity DataEC50:  460nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437878(CHEMBL2407929)
Affinity DataEC50:  20nMAssay Description:Agonist activity at recombinant human GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437878(CHEMBL2407929)
Affinity DataEC50:  57nMAssay Description:Agonist activity at recombinant human GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437890(CHEMBL2407936 | CHEMBL2407938)
Affinity DataEC50:  2.90E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437874(CHEMBL2407933)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437875(CHEMBL2407932)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437889(CHEMBL2407944)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437878(CHEMBL2407929)
Affinity DataEC50:  93nMAssay Description:Agonist activity at recombinant mouse GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437879(CHEMBL2408107)
Affinity DataEC50:  11nMAssay Description:Agonist activity at recombinant human GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437888(CHEMBL2407945)
Affinity DataEC50:  2.75E+3nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437890(CHEMBL2407936 | CHEMBL2407938)
Affinity DataEC50:  270nMAssay Description:Agonist activity at recombinant human GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataEC50:  500nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437885(CHEMBL2407949)
Affinity DataEC50:  880nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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