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Found 43 with Last Name = 'spyvee' and Initial = 'm'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119448(US8686018, 107)
Affinity DataKi:  8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119450(US8686018, 109)
Affinity DataKi:  8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119451(US8686018, 110)
Affinity DataKi:  10nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119449(US8686018, 108)
Affinity DataKi:  13nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119444(US8686018, 103)
Affinity DataKi:  14nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119446(US8686018, 105)
Affinity DataKi:  16nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119452(US8686018, 111)
Affinity DataKi:  26nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119445(US8686018, 104)
Affinity DataKi:  43nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119447(US8686018, 106)
Affinity DataKi:  50nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175652(CHEMBL200667 | Dodecanoic acid (S)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  80nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175656(CHEMBL200398 | Dodecanoic acid (S)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  160nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175653(CHEMBL200140 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  250nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  350nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473979(US10858344, Example 89)
Affinity DataIC50:  800nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473978(US10858344, Example 88)
Affinity DataIC50:  800nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175650(CHEMBL383597 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  900nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175655(CHEMBL372577 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  950nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175654(CHEMBL190383 | Tetradecanoic acid (R)-2-({2-[2-car...)
Affinity DataIC50:  1.25E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473988(US10858344, Example 99)
Affinity DataIC50:  1.25E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473973(US10858344, Example 81)
Affinity DataIC50:  1.30E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonistic activity at TLR in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473980(US10858344, Example 90)
Affinity DataIC50:  2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473977(US10858344, Example 87)
Affinity DataIC50:  2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473975(US10858344, Example 83)
Affinity DataIC50:  2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175658(CHEMBL200206 | Dodecanoic acid (R)-1-{2-[(R)-3-(hy...)
Affinity DataIC50:  2.15E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473976(US10858344, Example 84)
Affinity DataIC50:  2.50E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473974(US10858344, Example 82)
Affinity DataIC50:  3.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473987(US10858344, Example 98)
Affinity DataIC50:  3.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  3.07E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473983(US10858344, Example 93)
Affinity DataIC50:  3.75E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473986(US10858344, Example 96)
Affinity DataIC50:  4.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175657(CHEMBL380585 | N-(2-{[(R)-3-((R)-3-Dodecanoylamino...)
Affinity DataIC50:  5.20E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473982(US10858344, Example 92)
Affinity DataIC50:  6.25E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175656(CHEMBL200398 | Dodecanoic acid (S)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  6.46E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175652(CHEMBL200667 | Dodecanoic acid (S)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  6.90E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473989(US10858344, Example 100)
Affinity DataIC50:  1.40E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473990(US10858344, Example 101)
Affinity DataIC50:  2.00E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175653(CHEMBL200140 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  2.20E+4nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473985(US10858344, Example 95)
Affinity DataIC50: >2.50E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473991(US10858344, Example 102)
Affinity DataIC50: >2.50E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473992(US10858344, Example 106)
Affinity DataIC50:  1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473981(US10858344, Example 91)
Affinity DataIC50:  1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)

US Patent
LigandPNGBDBM473984(US10858344, Example 94)
Affinity DataIC50:  1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent