Affinity DataKi: 8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 10nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 13nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 14nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 16nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 26nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 43nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataKi: 50nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 800nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 800nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.25E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonistic activity at TLR in human PBMCMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 2.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 2.50E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 3.75E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 4.00E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 6.25E+3nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.40E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: >2.50E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: >2.50E+4nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
CV6 Therapeutics (NI)
US Patent
CV6 Therapeutics (NI)
US Patent
Affinity DataIC50: 1.50E+5nMAssay Description:The assay employs a DNA polymerase-based approach utilizing an oligonucleotide template with 3 distinct regions: a 3′ primer binding region, a ...More data for this Ligand-Target Pair