BindingDB PrimarySearch

Found 76 with Last Name = 'sriraman' and Initial = 'v'

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

IC50: 3.60nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510513(CHEMBL4531148)

IC50: 4.5nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510524(CHEMBL4525220)

IC50: 4.90nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510530(CHEMBL4449293)

IC50: 6nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510514(CHEMBL4453695)

IC50: 7.40nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510529(CHEMBL4453785)

IC50: 8.20nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510519(CHEMBL4463377)

IC50: 10nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510519(CHEMBL4463377)

IC50: 12nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510514(CHEMBL4453695)

IC50: 14nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510516(CHEMBL4531747)

IC50: 18nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510523(CHEMBL4440833)

IC50: 19nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510525(CHEMBL4444631)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510513(CHEMBL4531148)

IC50: 25nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510515(CHEMBL4579375)

IC50: 25nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510516(CHEMBL4531747)

IC50: 27nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510528(CHEMBL4586004)

IC50: 27nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510522(CHEMBL4472623)

IC50: 31nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510532(CHEMBL4584977)

IC50: 36nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510525(CHEMBL4444631)

IC50: 36nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510531(CHEMBL4579740)

IC50: 37nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510528(CHEMBL4586004)

IC50: 40nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510517(CHEMBL4459986)

IC50: 47nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510518(CHEMBL4470592)

IC50: 50nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510521(CHEMBL4460273)

IC50: 72nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510518(CHEMBL4470592)

IC50: 75nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510522(CHEMBL4472623)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510521(CHEMBL4460273)

IC50: 76nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510527(CHEMBL4474419)

IC50: 89nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510532(CHEMBL4584977)

IC50: 90nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510520(CHEMBL4587723)

IC50: 94nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510517(CHEMBL4459986)

IC50: 100nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510523(CHEMBL4440833)

IC50: 104nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510531(CHEMBL4579740)

IC50: 108nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510529(CHEMBL4453785)

IC50: 109nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510524(CHEMBL4525220)

IC50: 118nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Rattus norvegicus (Rat))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510514(CHEMBL4453695)

IC50: 130nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510515(CHEMBL4579375)

IC50: 140nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510520(CHEMBL4587723)

IC50: 160nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510527(CHEMBL4474419)

IC50: 180nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510526(CHEMBL4519645)

IC50: 220nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Homo sapiens (Human))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510526(CHEMBL4519645)

IC50: 230nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Rattus norvegicus (Rat))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510530(CHEMBL4449293)

IC50: 549nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Rattus norvegicus (Rat))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510513(CHEMBL4531148)

IC50: 640nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510513(CHEMBL4531148)

IC50: 1.40E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510524(CHEMBL4525220)

IC50: 2.00E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510530(CHEMBL4449293)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510529(CHEMBL4453785)

IC50: 2.04E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510514(CHEMBL4453695)

IC50: 3.69E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Rattus norvegicus (Rat))
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510525(CHEMBL4444631)

IC50: 4.30E+3nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

P2X purinoceptor 7(Mus musculus)
Emd Serono Research And Development Institute

Curated by ChEMBL

BDBM50510525(CHEMBL4444631)

IC50: 4.83E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

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