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Found 37 with Last Name = 'stables' and Initial = 'jp'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063800(3-(2-Piperidin-1-yl-ethyl)-6-propyl-3H-benzothiazo...)
Affinity DataKi:  0.600nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063807(3-(2-Piperidin-1-yl-ethyl)-6-propionyl-3H-benzothi...)
Affinity DataKi:  47nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063805(6-Benzoyl-3-(2-pyrrolidin-1-yl-ethyl)-3H-benzothia...)
Affinity DataKi:  54nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063801(3,6-Dipropionyl-3H-benzothiazol-2-one | CHEMBL1455...)
Affinity DataKi:  63nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063799(6-Benzyl-3-(2-morpholin-4-yl-ethyl)-3H-benzooxazol...)
Affinity DataKi:  72nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063804(3-(2-Piperidin-1-yl-ethyl)-6-propionyl-3H-benzooxa...)
Affinity DataKi:  72nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063806(6-Benzoyl-3-(2-dimethylamino-ethyl)-3H-benzooxazol...)
Affinity DataKi:  365nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063802(6-Propionyl-3-(2-pyrrolidin-1-yl-ethyl)-3H-benzoth...)
Affinity DataKi:  571nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain

Curated by ChEMBL
LigandPNGBDBM50063803(3-(2-Dimethylamino-ethyl)-6-pentanoyl-3H-benzothia...)
Affinity DataKi:  628nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330764(2-(4-Trifluoromethylphenyl)-4(5)-phenylimidazole |...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330765(2-Phenyl-4(5)-(3-chlorophenyl)imidazole | 4-(3-chl...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330763(2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM19187((2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of tetrodotoxin-sensitive Na+ channel at -50 mV membrane holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313459((Z)-4-oxo-4-(p-tolylamino)but-2-enoic acid | CHEMB...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50003655(Phenytoin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM19187((2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of tetrodotoxin-sensitive Na+ channel by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50031299(6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50003659(5H-dibenzo[b,f]azepine-5-carboxamide | CARBAMAZEPI...)
Affinity DataIC50:  1.31E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataIC50:  1.52E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50470610(CHEMBL340064)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313460((Z)-4-oxo-4-(phenylamino)but-2-enoic acid | CHEMBL...)
Affinity DataIC50:  2.03E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313458((Z)-4-(4-nitrophenylamino)-4-oxobut-2-enoic acid |...)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313456((Z)-methyl 4-(3,4-dichlorophenylamino)-4-oxobut-2-...)
Affinity DataIC50:  4.32E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313457((Z)-4-(2,6-dimethylphenylamino)-4-oxobut-2-enoic a...)
Affinity DataIC50:  4.34E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50470609(ADD-196022 | CHEMBL29740)
Affinity DataIC50:  4.89E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313454((E)-4-(4-chlorophenylamino)-4-oxobut-2-enoic acid ...)
Affinity DataIC50:  1.60E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313447(CHEMBL1086414 | Methyl N-(3,4-dimethylphenyl)fumar...)
Affinity DataIC50:  2.33E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313450((E)-4-(4-nitrophenylamino)-4-oxobut-2-enoic acid |...)
Affinity DataIC50:  2.56E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313453((E)-4-(3,4-dichlorophenylamino)-4-oxobut-2-enoic a...)
Affinity DataIC50:  4.38E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313451((E)-4-(3,4-dimethylphenylamino)-4-oxobut-2-enoic a...)
Affinity DataIC50:  7.55E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313448((E)-methyl 4-(3,4-dichlorophenylamino)-4-oxobut-2-...)
Affinity DataIC50: >8.00E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313452((E)-4-oxo-4-(p-tolylamino)but-2-enoic acid | 4-oxo...)
Affinity DataIC50:  8.35E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313455((Z)-methyl 4-oxo-4-(p-tolylamino)but-2-enoate | CH...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University

Curated by ChEMBL
LigandPNGBDBM50313449((E)-methyl 4-(4-chlorophenylamino)-4-oxobut-2-enoa...)
Affinity DataIC50:  4.00E+8nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed