Affinity DataKi: 0.0600nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of pig plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of pig plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of recombinant mouse C-terminal 6His-tagged plasma kallikrein (20 to 638 residues) using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrat...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of recombinant mouse C-terminal 6His-tagged plasma kallikrein (20 to 638 residues) using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrat...More data for this Ligand-Target Pair