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Found 94 with Last Name = 'stake' and Initial = 'ge'
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13433(N-[(3S)-2-[(tert-butoxy)carbonyl]-3-(methylcarbamo...)
Affinity DataKi:  2.40E+4nM ΔG°:  -26.1kJ/molepH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13529(N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid...)
Affinity DataKi: >5.00E+5nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188792(CHEMBL213750 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188795(CHEMBL386550 | ammonium N-{4-[2,2-bis(3-methyl-1,2...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188775(CHEMBL214192 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  80nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188791(CHEMBL213732 | ammonium N-{4-[2,2-bis(3-methyl-1,2...)
Affinity DataIC50:  80nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188801(CHEMBL213620 | ammonium N-{4-[2-(2-{[(tert-butoxy)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188797(CHEMBL213802 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188781(CHEMBL209527 | ammonium N-(4-{2-[(4-carboxyphenyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188780(CHEMBL211786 | ammonium N-(4-{2-[3-(benzenesulfony...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188778(CHEMBL213626 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188782(CHEMBL384201 | ammonium N-{4-[3-(3-cyanophenyl)-2,...)
Affinity DataIC50:  210nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188779(CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(met...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188783(CHEMBL213226 | ammonium N-{4-[3-(3-methoxyphenyl)-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188798(CHEMBL385818 | ammonium N-(4-{2-[(benzyloxy)methyl...)
Affinity DataIC50:  270nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188794(CHEMBL380374 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  290nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188793(CHEMBL209957 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  300nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188776(4-(2-benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopro...)
Affinity DataIC50:  320nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188796(CHEMBL213728 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  330nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188785(CHEMBL209955 | ammonium N-{4-[3-(4-methoxyphenyl)-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188786(CHEMBL213826 | ammonium N-{4-[6-methoxy-2,2-bis(me...)
Affinity DataIC50:  380nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188799(CHEMBL213727 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  390nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188777(CHEMBL213452 | ammonium N-[4-(2-{[(benzyloxy)carbo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188800(CHEMBL386657 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  410nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188788(CHEMBL214241 | ammonium N-{4-[2-(3-methanesulfonyl...)
Affinity DataIC50:  420nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188789(CHEMBL378337 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  430nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188802(CHEMBL210180 | ammonium N-[4-(2-{[(tert-butoxy)car...)
Affinity DataIC50:  450nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188787(CHEMBL213594 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  570nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188776(4-(2-benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopro...)
Affinity DataIC50:  900nMAssay Description:Inhibition HPTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188790(CHEMBL209492 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HPTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13462(3-{3-[(3S)-3-(methylcarbamoyl)-7-(sulfoamino)-1,2,...)
Affinity DataIC50:  2.50E+3nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13461(N-[(3S)-3-(methylcarbamoyl)-2-{3-[3-(sulfoamino)ph...)
Affinity DataIC50:  4.80E+3nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188779(CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(met...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of HCPTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188776(4-(2-benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopro...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of HCPTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13452(N-[(3S)-2-[(tert-butoxy)carbonyl]-3-(3-methyl-1,2,...)
Affinity DataIC50:  8.23E+3nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188777(CHEMBL213452 | ammonium N-[4-(2-{[(benzyloxy)carbo...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of TCPTP38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188779(CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(met...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13451(N-[(3S)-2-[(tert-butoxy)carbonyl]-3-[(2-methylprop...)
Affinity DataIC50:  1.67E+4nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13450(N-[(3S)-2-[(tert-butoxy)carbonyl]-3-(methoxycarbon...)
Affinity DataIC50:  1.90E+4nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188776(4-(2-benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopro...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13446(Tetrahydroisoquinoline (TIQ) deriv. 8m | ammonium ...)
Affinity DataIC50:  2.49E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13464(N-(3-{3-oxo-3-[7-(sulfoamino)-1,2,3,4-tetrahydrois...)
Affinity DataIC50:  2.60E+4nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13463(N-{3-[2-({[3-(sulfoamino)phenyl]methyl}carbamoyl)e...)
Affinity DataIC50:  3.35E+4nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13445(Tetrahydroisoquinoline (TIQ) deriv. 8l | ammonium ...)
Affinity DataIC50:  3.67E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13444(Tetrahydroisoquinoline (TIQ) deriv. 8k | ammonium ...)
Affinity DataIC50:  3.70E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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