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Found 80 with Last Name = 'steed' and Initial = 'p'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  2nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  4nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  7nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  8nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  14nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  16nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206156(CHEMBL246240 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  32nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  36nMAssay Description:Inhibition of HSP90-mediated Erk phosphorylation in human AU565 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  41nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480374(CHEMBL560955)
Affinity DataIC50:  46nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  61nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379848(CHEMBL2011850)
Affinity DataIC50:  401nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480372(CHEMBL562990)
Affinity DataIC50:  490nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379854(CHEMBL2011855)
Affinity DataIC50:  498nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379841(CHEMBL2011843)
Affinity DataIC50:  568nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206153(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379845(CHEMBL2011847)
Affinity DataIC50:  665nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379840(CHEMBL2011853)
Affinity DataIC50:  705nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379842(CHEMBL2011845)
Affinity DataIC50:  731nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206155(CHEMBL246031 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206159(4-fluoro-N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]imidazo...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206154(CHEMBL245623 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480395(CHEMBL559840)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480380(CHEMBL552300)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480373(CHEMBL563335)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379843(CHEMBL2011846)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379849(CHEMBL2011851)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379857(CHEMBL2011858)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379855(CHEMBL2011856)
Affinity DataIC50:  4.51E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379852(CHEMBL2011844)
Affinity DataIC50:  5.81E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480371(CHEMBL554288)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379846(CHEMBL2011848)
Affinity DataIC50:  7.37E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379847(CHEMBL2011849)
Affinity DataIC50:  7.75E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480393(CHEMBL563500)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50379851(CHEMBL2011842)
Affinity DataIC50:  9.97E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480370(CHEMBL562929)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480368(CHEMBL559642)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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