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Found 201 with Last Name = 'stefany' and Initial = 'd'
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-methylhistamine from rat histamine H3 receptor (445 amino acid residues) transfected in human 293 cells after 1 hr by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443216(CHEMBL3087667)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443227(CHEMBL3087356)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443226(CHEMBL3087357)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443225(CHEMBL3087671)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443224(CHEMBL3087670)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443223(CHEMBL3087358)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443222(CHEMBL3087673)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200837(2-[2-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  4.21nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443221(CHEMBL3087668)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443220(CHEMBL3087359)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443219(CHEMBL3087672)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200827(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  7.10nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200831(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  7.57nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443218(CHEMBL3087360)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200828(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  17.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200833(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  22.3nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200830(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  26.3nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200815(1 2-[2-Methyl-6-((2S,3′R)-2-methyl-[1,3̸...)
Affinity DataKi:  37.6nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200829(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  38.9nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200832(2-[2-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  48.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200823(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  56.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200821(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  95.1nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200836(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  95.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200834(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  105nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM200822(8-hydroxy-2-[2-methyl-6-((2s,3'r)-2-methyl-[1,...)
Affinity DataKi:  267nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417722(CHEMBL1644207)
Affinity DataIC50:  0.0200nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417777(CHEMBL1644214)
Affinity DataIC50:  0.0501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417721(CHEMBL1644206)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417759(CHEMBL1644213)
Affinity DataIC50:  0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417747(CHEMBL1644245)
Affinity DataIC50:  0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417725(CHEMBL1644211)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417764(CHEMBL1644227)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417771(CHEMBL1644247)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417723(CHEMBL1644208)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417726(CHEMBL1644212)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417773(CHEMBL1644253)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417728(CHEMBL1644217)
Affinity DataIC50:  0.794nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417763(CHEMBL1644224)
Affinity DataIC50:  0.891nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417754(CHEMBL1644255)
Affinity DataIC50:  2.29nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417778(CHEMBL1644260)
Affinity DataIC50:  2.29nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417774(CHEMBL1644256)
Affinity DataIC50:  2.57nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417767(CHEMBL1644235)
Affinity DataIC50:  2.57nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417719(CHEMBL1644204)
Affinity DataIC50:  2.69nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417768(CHEMBL1644238)
Affinity DataIC50:  2.88nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417760(CHEMBL1644216)
Affinity DataIC50:  3.63nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417744(CHEMBL1644240)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417749(CHEMBL1644248)
Affinity DataIC50:  4.47nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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