Compile Data Set for Download or QSAR
maximum 50k data
Found 32 with Last Name = 'steiger' and Initial = 'd'
LigandPNGBDBM50331290(CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331290(CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331285(2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331285(2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...)
Affinity DataIC50:  2.36E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305208(3-Methyl-4-phenylbut-3-en-2-one oxime | CHEMBL6037...)
Affinity DataIC50:  2.70E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305207(4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime | ...)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  3.34E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054758(CHEMBL357130 | [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  5.63E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054758(CHEMBL357130 | [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  5.96E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  8.93E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataIC50:  1.16E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)
Affinity DataIC50:  1.23E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataIC50:  1.24E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)
Affinity DataIC50:  1.31E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)
Affinity DataIC50:  2.15E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331287(CHEMBL1289952 | ethyl 2-(5-(benzyloxy)-1H-indol-3-...)
Affinity DataIC50:  2.16E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)
Affinity DataIC50:  2.27E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331287(CHEMBL1289952 | ethyl 2-(5-(benzyloxy)-1H-indol-3-...)
Affinity DataIC50:  2.88E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)
Affinity DataIC50:  3.04E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)
Affinity DataIC50:  3.22E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305199(3-Methyl-4-m-tolyl-but-3-en-2-one oxime | CHEMBL58...)
Affinity DataEC50:  1.44E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305205(3-[4-(Dimethylamino)phenyl]acrylaldehyde oxime | C...)
Affinity DataEC50:  1.59E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305202(CHEMBL589873 | alpha-Methylcinnamaldoxime)
Affinity DataEC50:  6.94E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305201((1Z,2E)-3-(4-chlorophenyl)acrylaldehyde oxime | CH...)
Affinity DataEC50:  9.40E+3nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305200(3-Buten-2-one, 4-(4-chlorophenyl)-, oxime(2E, 3E) ...)
Affinity DataEC50:  2.76E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305206(4-(Benzo[d][1,3]-dioxol-5-yl)-3-beuten-2-one oxime...)
Affinity DataEC50:  1.15E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305204((2E,3E)-4-(3-chlorophenyl)but-3-en-2-one oxime | C...)
Affinity DataEC50:  6.31E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)
Affinity DataEC50:  5.14E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305198(4-(4-Methoxy-phenyl)-3-methyl-but-3-en-2-one oxime...)
Affinity DataEC50:  4.61E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305203(4-Phenyl-but-3-en-2-one oxime | CHEMBL589794)
Affinity DataEC50:  9.66E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed