Affinity DataKi: 0.0520nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.106nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.112nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.132nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.183nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.191nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.285nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.313nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.361nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.393nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.707nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YYMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.829nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YYMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity of the compound at cloned Neuropeptide Y receptor type 1 expressed in AV-12 cells is evaluated.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 3.98nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair