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Found 124 with Last Name = 'stenmark' and Initial = 'hg'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177621((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-thiomo...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177626(3-(benzo[d]oxazol-6-yl)-4-(3-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177626(3-(benzo[d]oxazol-6-yl)-4-(3-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177629(3-(2-cyclopropylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tet...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178254(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(1-methyl-1,2...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177621((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-thiomo...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177618(3-(2,3-dihydrobenzofuran-6-yl)-4-(3-(3-(5,6,7,8-te...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177636(3-(quinolin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177616((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-morpho...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177622(3-(pyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-n...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177616((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-morpho...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177640(3-(6-methoxypyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177624(3-(3-fluorophenyl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177627((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-methox...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178253(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  1.18nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178243(3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177617(3-(1-phenyl-1H-pyrazol-4-yl)-4-(3-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177629(3-(2-cyclopropylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178245(3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.22nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178242(3-(6-methoxypyridin-3-yl)-4-(2-(3-(5,6,7,8-tetrahy...)
Affinity DataIC50:  1.23nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178255(3-(6-methoxypyridin-3-yl)-4-(2-(3-(1-methyl-1,2,3,...)
Affinity DataIC50:  1.24nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178247((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-(pyrro...)
Affinity DataIC50:  1.26nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177637(3-(2-methylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  1.28nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177629(3-(2-cyclopropylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.43nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178248(3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  1.54nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178250((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-morpho...)
Affinity DataIC50:  1.56nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177622(3-(pyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-n...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178257((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-thiomo...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177639(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(1-methyl-1,2...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177624(3-(3-fluorophenyl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  1.75nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178240(3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  1.77nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177634(3-phenyl-4-(3-(3-(5,6,7,8-tetrahydro-1,8-naphthyri...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177632((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-methyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178238(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...)
Affinity DataIC50:  2.09nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177630(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(6-(methylami...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177618(3-(2,3-dihydrobenzofuran-6-yl)-4-(3-(3-(5,6,7,8-te...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178241(CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...)
Affinity DataIC50:  2.17nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177619((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(pyridin-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Integrin alphav-beta1 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177626(3-(benzo[d]oxazol-6-yl)-4-(3-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of Integrin alphav-beta1 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178239(3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178252(3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...)
Affinity DataIC50:  2.82nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177621((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-thiomo...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178256(3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-(pyrrolidin-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177630(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(6-(methylami...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177622(3-(pyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-n...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50:  3.49nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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