Affinity DataIC50: 0.320nMAssay Description:Inhibitory activity of the compound against renin was determinedMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 16.4nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 34.2nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 94.6nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 176nMAssay Description:TP_TRANSPORTER: drug resistance(Imatinib mesylate) in BCRP-expressing SaoS2 cellsMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of Serratia marcescens IMP1 expressed in Escherichia coli BL21(DE3) using chromacef as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 289nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa VIM2 expressed in Escherichia coli BL21(DE3) using chromacef as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 3.03E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.54E+5nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair