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Found 52 with Last Name = 'stichel' and Initial = 'j'
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  0.0631nMAssay Description:Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  6.30nMAssay Description:Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  6.30nMAssay Description:Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)
Affinity DataIC50:  2.51E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)
Affinity DataIC50:  2.70E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)
Affinity DataIC50:  3.80E+3nMAssay Description:Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)
Affinity DataIC50:  3.80E+3nMAssay Description:Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563420(CHEMBL4780125)
Affinity DataIC50:  3.98E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563420(CHEMBL4780125)
Affinity DataIC50:  4.00E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.0398nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY1 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.0631nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY2 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  3.20nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY5 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.400nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  845nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.501nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  5.01E+3nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581650(CHEMBL5081975)
Affinity DataEC50:  9nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581651(CHEMBL5077507)
Affinity DataEC50:  195nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581652(CHEMBL5085505)
Affinity DataEC50:  280nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581653(CHEMBL5089041)
Affinity DataEC50:  564nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581654(CHEMBL5082551)
Affinity DataEC50:  20nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581655(CHEMBL5080998)
Affinity DataEC50:  32nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581656(CHEMBL5082981)
Affinity DataEC50:  966nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581657(CHEMBL5088494)
Affinity DataEC50:  64nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581658(CHEMBL5092307)
Affinity DataEC50:  6nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581650(CHEMBL5081975)
Affinity DataEC50:  9.5nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581651(CHEMBL5077507)
Affinity DataEC50:  195nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581652(CHEMBL5085505)
Affinity DataEC50:  282nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581653(CHEMBL5089041)
Affinity DataEC50:  562nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581654(CHEMBL5082551)
Affinity DataEC50:  20nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581655(CHEMBL5080998)
Affinity DataEC50:  32nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581656(CHEMBL5082981)
Affinity DataEC50:  955nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581657(CHEMBL5088494)
Affinity DataEC50:  65nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581658(CHEMBL5092307)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581650(CHEMBL5081975)
Affinity DataEC50:  134nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581656(CHEMBL5082981)
Affinity DataEC50:  513nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581657(CHEMBL5088494)
Affinity DataEC50:  150nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581658(CHEMBL5092307)
Affinity DataEC50:  39nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581650(CHEMBL5081975)
Affinity DataEC50:  135nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581656(CHEMBL5082981)
Affinity DataEC50:  513nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581657(CHEMBL5088494)
Affinity DataEC50:  151nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  5.10E+3nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  794nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.398nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.0398nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  443nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  4.5nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChemerin-like receptor 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50581658(CHEMBL5092307)
Affinity DataEC50:  39nMAssay Description:Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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